Nick Holford

866 messages, 1994–2025

Date Subject
? Graphing NONMEM output with EXCEL Macro technical
? f2c - FORTRAN to C technical
? FORTRAN compilers on Pentium machines technical
? PK Analysis in Toxicokinetic Studies technical
Aug 04, 1994 Modeling Rates and Effects of Drug X technical
Sep 29, 1994 How to Output the Objective Function to a Separate File technical
Nov 14, 1994 General Question about the 'Best' Platform for NONMEM technical
Nov 23, 1994 General Question about the 'Best' Platform for NONMEM technical
Dec 01, 1994 Prediction Curve technical
Mar 28, 1995 NONMEM using OS/2 Warp technical
Jul 04, 1996 Re: NONMEM in drug development technical
Jul 11, 1996 Re: NONMEM in drug development -Reply technical
Aug 25, 1996 Re: LOG(F) Error Model/Machine Differences technical
Aug 31, 1996 Re: LOG(F) error model technical
Sep 04, 1996 Re: More about LOG(F) technical
Sep 24, 1996 Re: kinetic interpolation and effect compartments technical
Sep 25, 1996 Re: kinetic interpolation and effect compartments technical
Sep 25, 1996 Re: using CLS with Differential Equations technical
Sep 26, 1996 Re: Linear vs curvy splines technical
Apr 29, 1997 Re: fortran compiler technical
May 20, 1997 Re: Concentration values below assay limits technical
May 21, 1997 Re: Concentration values below assay limits technical
Oct 21, 1997 Re: Units for Vmax technical
Nov 23, 1997 Re: Multiprocessor PC, NT, pcANYWHERE technical
Jan 08, 1998 Re: Bootstrap sampling technical
Feb 04, 1998 Re: Best Fortran compiler? technical
Jul 23, 1998 help with ALPHA compiler please technical
Aug 04, 1998 Re: RE: multitasking technical
Sep 16, 1998 Re: Nonmem and Fortran under Windows NT technical
Oct 15, 1998 Modelling Workshop event
Dec 04, 1998 Re: RE: NONMEM as a dll technical
Dec 11, 1998 Re: 2 comp MM technical
Mar 04, 1999 Re: centering variables technical
Mar 25, 1999 Re: comparing theta's technical
Mar 29, 1999 Re: comparing theta's technical
Apr 02, 1999 Re: flip-flop kinetics technical
Oct 17, 1999 Re: Modification of the File, nmfe5.bat? technical
Nov 12, 1999 Re: Standard error of 'secondary' parameters technical
Nov 12, 1999 Re: Standard error of 'secondary' parameters technical
Nov 17, 1999 Covariate Models Using Weight (origination of the above four threads) technical
Nov 17, 1999 Covariate Models Using Weight technical
Nov 17, 1999 Re: repeating cases technical
Nov 18, 1999 Re: Covariate Models Using Weight technical
Nov 18, 1999 Re: Covariate Models Using Weight technical
Nov 22, 1999 Re: Covariate Models Using Weight technical
Nov 29, 1999 Citations in the NONMEM Users Archive news
Dec 13, 1999 Re: metabolite modeling technical
Dec 17, 1999 Re: metabolite modeling technical
Jan 11, 2000 NONMEM Installation technical
Feb 05, 2000 Re: Coding problem technical
Apr 24, 2000 Re: Model building algorithm technical
May 31, 2000 Re: Software and procedures for conducting and reporting on NONMEM analyses in clinical reports technical
Aug 04, 2000 [Fwd: CLIN PHAR STAT: Mixed Vs Fixed] technical
Aug 07, 2000 Re: [Fwd: CLIN PHAR STAT: Mixed Vs Fixed] technical
Aug 08, 2000 Re: [Fwd: CLIN PHAR STAT: Mixed Vs Fixed] technical
Aug 09, 2000 Re: [Fwd: CLIN PHAR STAT: Mixed Vs Fixed] technical
Aug 26, 2000 Warning: NMTRAN does not interpret conditional abbreviated code properly technical
Sep 11, 2000 Missing data values technical
Sep 13, 2000 Re: Initial conditions for amounts in compartments technical
Sep 15, 2000 Re: Out of Environment Space technical
Sep 22, 2000 Re: FW: FORTRAN compiler for use with NONMEM technical
Sep 23, 2000 Re: Weight as Covariate technical
Sep 29, 2000 Re: Bayesian estimation technical
Oct 19, 2000 Re: win 2000 technical
Nov 13, 2000 Re: 95% CI of paramter estimate technical
Nov 14, 2000 Re: msg from atul technical
Nov 17, 2000 Re: 95% CI of parameter estimate technical
Nov 27, 2000 Re: fortran question technical
Nov 27, 2000 Re: Rate constants technical
Jan 12, 2001 Re: Question for Non-Compartment Anaylsis technical
Feb 06, 2001 Re: Reading NONMEM output into S-Plus technical
Mar 09, 2001 Re: WinNonlin compatible with DVF ? technical
Mar 24, 2001 Re: Bootstrap resampling! technical
Mar 27, 2001 Re: Bootstrap resampling! technical
Mar 29, 2001 Re: Bootstrap resampling! technical
Mar 29, 2001 Re: Bootstrap resampling! -> Randomization test technical
Mar 30, 2001 Re: Bootstrap resampling! -> Randomization test technical
May 07, 2001 Re: Unreasonable VSS estimate technical
May 07, 2001 Re: NONMEM priority on windows NT/2000 technical
May 08, 2001 Re: NONMEM priority on windows NT/2000 technical
May 09, 2001 Re: Parameterization!!! technical
May 10, 2001 Re: Parameterization!!! technical
May 10, 2001 Re: Parameterization!!! technical
May 24, 2001 Re: Error models and weighting technical
May 28, 2001 Re: Slow Gradient Method. technical
May 31, 2001 Re: Slow Gradient Method. technical
Jul 02, 2001 Centering (was Re: Missing covariates) technical
Jul 03, 2001 Re: Centering (was Re: Missing covariates) technical
Jul 04, 2001 Re: Centering (was Re: Missing covariates) technical
Jul 05, 2001 Re: Centering (was Re: Missing covariates) technical
Jul 05, 2001 Re: Centering (was Re: Missing covariates) technical
Jul 05, 2001 Re: 70kg neonates technical
Aug 14, 2001 Re: Rounding Error 134 technical
Aug 15, 2001 Re: $SIMULATION technical
Aug 16, 2001 Re: MSDOS versus VisualNM technical
Aug 20, 2001 Re: NONMEM random number generator technical
Aug 20, 2001 Re: weighting technical
Aug 20, 2001 Re: Help: Non-positive semi-definite message technical
Aug 21, 2001 Re: Help: Non-positive semi-definite message technical
Aug 21, 2001 Re: Help: Non-positive semi-definite message technical
Sep 17, 2001 Re: 1 binary response/person technical
Oct 01, 2001 Re: Coadministered drugs (PK-PD) technical
Oct 02, 2001 Re: Non-zero peripheral drug amount technical
Oct 04, 2001 Pharmacokinetics, allometry and flat earth theories technical
Oct 10, 2001 Re: Post treatment effect technical
Oct 15, 2001 Re: Distributive Computing technical
Oct 29, 2001 Re: Weight normailized doses in modeling technical
Nov 02, 2001 NONMEM Zoo technical
Nov 07, 2001 Re: Bayesian fits technical
Nov 13, 2001 Re: 3 compartment nonlinear pharmacokinetics model technical
Nov 15, 2001 Re: 3 compartment nonlinear pharmacokinetics model technical
Jan 24, 2002 Re: NONMEM crash? technical
Jan 25, 2002 Re: max no. of observation per subject technical
Feb 02, 2002 Re: SUBROUTINE GETETA NOT INITIALIZED (ERROR MESSAGE) technical
Feb 02, 2002 Re: SUBROUTINE GETETA NOT INITIALIZED (ERROR MESSAGE) technical
Feb 04, 2002 Re: Parallel absorption model (two lag times) technical
Feb 19, 2002 Re: Modeling of Blood flow data technical
Feb 28, 2002 Re: Dumping of internally used parameter values to file technical
Mar 08, 2002 Re: Error message (continued..) technical
Mar 08, 2002 Re: T matrix technical
Mar 09, 2002 Re: T matrix technical
Mar 11, 2002 Re: T matrix technical
Mar 12, 2002 Re: NONMEM SE and CI technical
Mar 19, 2002 Re: Problems with Digital Visual Fortran vers 5.0 on Windows NT 4.0 technical
Mar 20, 2002 Re: Digital Visual Fortran vers 5.0 vs 6.6 technical
Apr 02, 2002 RE: Simultaneous modeling of PK and categorical PD technical
Apr 02, 2002 Re: Simultaneous modeling of PK and categorical PD technical
Apr 03, 2002 Simultaneous Continuous and Categorical Modelling technical
Apr 18, 2002 Re: covariate significance technical
Apr 20, 2002 Re: NMTRAN data truncation technical
Apr 23, 2002 Re: Re: nonmem technical
Apr 29, 2002 Re: NONMEM runtimes technical
May 17, 2002 Re: Placebo-corrected PD models technical
Jun 12, 2002 Re: NONMEM help under Windows XP technical
Jul 11, 2002 Re: Storing simulations technical
Jul 11, 2002 Re: Storing simulations technical
Jul 29, 2002 Re: Cl/F and V/F technical
Jul 30, 2002 Re: Missing Gender (Categorical values) technical
Jul 30, 2002 Not enough sex! technical
Jul 30, 2002 Re: Missing Gender (Categorical values) technical
Jul 31, 2002 Re: Missing Gender (Categorical values) technical
Aug 06, 2002 Portland Group f77 compiler technical
Aug 06, 2002 Compaq Visual Fortran compared to Gnu g77 compiler technical
Aug 19, 2002 Re: Confidence interval technical
Sep 18, 2002 Re: Error Message from NONMEM :: MINIMIZATION TERMINATED (ERROR=136) technical
Sep 28, 2002 Nick Holford technical
Oct 02, 2002 Re: OMEGA HAS A NONZERO BLOCK technical
Oct 02, 2002 Re: OMEGA HAS A NONZERO BLOCK technical
Oct 04, 2002 Re: FW: OMEGA HAS A NONZERO BLOCK technical
Oct 04, 2002 Re: FW: OMEGA HAS A NONZERO BLOCK technical
Oct 04, 2002 Re: OMEGA HAS A NONZERO BLOCK technical
Oct 07, 2002 Re: OMEGA HAS A NONZERO BLOCK technical
Oct 07, 2002 Re: OMEGA HAS A NONZERO BLOCK technical
Oct 08, 2002 Re: signficant covariate question technical
Oct 08, 2002 Re: OMEGA HAS A NONZERO BLOCK technical
Dec 01, 2002 Intel Fortran 7 Compiler technical
Dec 02, 2002 Re: When to study BOV? technical
Jan 09, 2003 Re: intel 7.0 on linux --> see Nick Holfords email on Intel 7.0 for windows technical
Feb 14, 2003 Re: simulated negative concentration technical
Feb 17, 2003 Re: Michaelis-Menten model i nonmem technical
Mar 12, 2003 Re: separate parameter estimates technical
Mar 13, 2003 Date:Thursday, MarchRe: Ln(DV 13, 2003 2:57 PM technical
Mar 27, 2003 Re: Describing variability technical
Mar 31, 2003 Re: Describing variability technical
Apr 11, 2003 Re: Error model technical
Apr 11, 2003 Re: Error model technical
Apr 27, 2003 Re: Covariate analysis technical
May 05, 2003 Re: Using covariates with positive and negative values technical
May 12, 2003 Correction to 1999 posting on between occasion variability technical
May 20, 2003 Re: DV Simulation technical
May 29, 2003 Re: DV Simulation technical
May 29, 2003 Re: DV Simulation technical
May 29, 2003 Re: DV Simulation technical
May 29, 2003 Re: DV Simulation technical
May 30, 2003 Re: DV Simulation technical
Jun 02, 2003 Re: Obj. function is infinite (error=136) technical
Jun 05, 2003 Re: DV Simulation technical
Jun 09, 2003 Re: WFN for UNIX/Linux news
Jun 13, 2003 Re: Watcom compiler technical
Jun 30, 2003 RE: Hessians of posterior density technical
Jul 16, 2003 Re: Re: FO vs FOCE vs LAPLACIAN technical
Jul 18, 2003 Re: Re: FO vs FOCE vs LAPLACIAN technical
Jul 22, 2003 Re: FO vs FOCE vs LAPLACIAN technical
Aug 07, 2003 Re: TVKa>TVKe or Ka>Ke? technical
Aug 18, 2003 Re: Simultaneous Running of nmfe5 technical
Oct 09, 2003 Re: Two simple questions technical
Oct 13, 2003 RE: modeling compartments within compartments technical
Oct 21, 2003 Re: LLR test, AIC, BIC technical
Oct 22, 2003 Re: Filing technical
Oct 22, 2003 Re: LLR test, AIC, BIC technical
Oct 22, 2003 Re: LLR test, AIC, BIC technical
Nov 17, 2003 Re: Different population estimates technical
Nov 18, 2003 RE: modeling interoccasion variability technical
Dec 17, 2003 Re: Scaling of pharmacokinetics in peds technical
Dec 19, 2003 Re: Scaling of pharmacokinetics in peds technical
Dec 20, 2003 Re: Scaling of pharmacokinetics in peds technical
Feb 09, 2004 Re: Time of day as a covariate technical
Feb 11, 2004 Re: Number of compartments technical
Feb 11, 2004 some issues about NONMEM technical
Feb 11, 2004 some issues about NONMEM technical
Feb 12, 2004 some issues about NONMEM technical
Feb 14, 2004 Re: ADVAN2 and ADVAN6: biased results technical
Mar 14, 2004 RE: FWORK ERROR technical
Mar 20, 2004 RE: time-controlled drug delivery technical
Mar 29, 2004 RE: Combined tissue and plasma concentration models technical
Apr 08, 2004 RE: Trouble with Verbatim code technical
Apr 19, 2004 Suggestions for the Official Bug List news
Apr 20, 2004 RE: no. of dummy points affect simulation and estimation results technical
May 23, 2004 RE: Multiple Dosing technical
May 24, 2004 RE: Fx technical
May 25, 2004 RE: Fx technical
May 30, 2004 RE: PK models for rich and sparse sampling technical
Jun 01, 2004 RE: $OMEGA blocks and log-likelihood profiling technical
Jun 01, 2004 RE: $OMEGA blocks and log-likelihood profiling technical
Jun 01, 2004 RE:info on a do-while-loop technical
Jun 03, 2004 RE: $OMEGA blocks and log-likelihood profiling technical
Jun 05, 2004 RE: $OMEGA blocks and log-likelihood profiling technical
Jun 10, 2004 RE: How sparse is too sparse? technical
Jun 10, 2004 RE: $OMEGA blocks and log-likelihood profiling technical
Jun 10, 2004 RE: $OMEGA blocks and log-likelihood profiling technical
Jun 11, 2004 RE: $OMEGA blocks and log-likelihood profiling technical
Jun 28, 2004 RE: Coding for missing data values technical
Jun 28, 2004 RE: Coding for missing data values technical
Jun 29, 2004 RE: Coding for missing data values technical
Jun 29, 2004 RE: Coding for missing data values technical
Jun 30, 2004 RE: $OMEGA blocks and log-likelihood profiling technical
Jul 29, 2004 RE: calculation of time-to-nadir technical
Jul 30, 2004 RE: calculation of time-to-nadir technical
Aug 03, 2004 RE: calculation of time-to-nadir technical
Aug 11, 2004 RE: Modeling of iv and po data technical
Aug 18, 2004 RE: indirect response model technical
Sep 06, 2004 RE: NONMEM dataset development technical
Sep 07, 2004 RE: NONMEM dataset development technical
Sep 15, 2004 RE: covariates technical
Sep 16, 2004 RE: covariates technical
Sep 16, 2004 RE: covariates technical
Sep 16, 2004 RE: covariates technical
Sep 17, 2004 RE: covariates technical
Sep 17, 2004 RE: covariates technical
Sep 18, 2004 RE: covariates technical
Sep 20, 2004 RE: covariates technical
Sep 20, 2004 RE: BOV technical
Sep 21, 2004 RE: BOV technical
Sep 21, 2004 RE: BOV technical
Sep 21, 2004 RE: BOV technical
Sep 22, 2004 RE: BOV technical
Sep 22, 2004 RE: BOV technical
Sep 22, 2004 RE: BOV technical
Sep 22, 2004 RE: BOV technical
Sep 23, 2004 RE: BOV technical
Oct 05, 2004 RE: saturable first-pass metabolism technical
Oct 07, 2004 Avoiding ABORT in NONMEM Initialization technical
Oct 18, 2004 RE: allometric scaling technical
Oct 27, 2004 RE: Missing Covariate values technical
Nov 12, 2004 RE: Open note to Nick Holford about WFN installation subdirectories news
Nov 22, 2004 RE: When should a long run be aborted? technical
Nov 22, 2004 RE: Simulation problem technical
Nov 22, 2004 RE: Simulation problem technical
Nov 25, 2004 RE: PD lag time in $DES technical
Nov 25, 2004 RE: Negative values in 95%CI on ETAs technical
Nov 26, 2004 RE: Permutation test with small number of possible permutations technical
Nov 29, 2004 RE: Model estimate of dose technical
Nov 30, 2004 RE: problem with simulation technical
Dec 07, 2004 Re: posthoc step technical
Dec 07, 2004 RE: Model estimate of dose technical
Dec 07, 2004 Re: SAS program or SAS macro to prepare NonMem ready data technical
Dec 08, 2004 Re: SAS program or SAS macro to prepare NonMem ready data technical
Dec 08, 2004 Re: posthoc step technical
Dec 08, 2004 Re: posthoc step technical
Dec 09, 2004 Re: posthoc step technical
Dec 14, 2004 Re: posthoc step technical
Dec 15, 2004 Re: posthoc step technical
Dec 16, 2004 Re: posthoc step technical
Dec 21, 2004 Re: How does NONMEM $DES work? technical
Dec 22, 2004 Re: How does NONMEM $DES work? technical
Jan 04, 2005 Re: MSFI issue - apparent state: unit 3 named technical
Feb 17, 2005 Re: New NMTRAN bug list with a new Bug # XXVIII news
Feb 28, 2005 Re: Model building question technical
Feb 28, 2005 Re: Model building question technical
Mar 01, 2005 Re: Model building question technical
Mar 04, 2005 RE: Plcebo Corrected PK/PD technical
Mar 04, 2005 Re: Plcebo Corrected PK/PD technical
Mar 04, 2005 Re: Plcebo Corrected PK/PD technical
Mar 04, 2005 Re: Plcebo Corrected PK/PD technical
Mar 05, 2005 Re: Plcebo Corrected PK/PD technical
Mar 15, 2005 Re: Modeling of different formulations technical
Mar 25, 2005 Re: Revised NMTRAN buglist [14MAR2005] technical
Apr 04, 2005 Re: population size and confidence power technical
Apr 04, 2005 Re: population size and confidence power technical
Apr 16, 2005 Re: Residuals and INTERACTION for simultaneous PK/PD,impossible? technical
Apr 22, 2005 Re: addition of dummy points technical
May 03, 2005 Re: Missing mixed continuous and categorical data technical
May 04, 2005 Re: Iterative Two Stage Bayesian in NONMEM technical
May 05, 2005 Re: SD values technical
May 17, 2005 Re: Probabilistic model technical
May 17, 2005 Re: Probabilistic model technical
May 18, 2005 Re: Probabilistic model technical
May 19, 2005 Re: Probabilistic model technical
May 19, 2005 Re: Need help technical
May 19, 2005 Re: Probabilistic model technical
May 26, 2005 CONT data item tip technical
May 27, 2005 Re: NONMEM Tips #21 - What Bill didn't tell you technical
Jun 03, 2005 Re: What does nonmem do after iteration stops? technical
Jun 14, 2005 Re: Simulation vs. actual data technical
Jun 25, 2005 Re: Simulation vs. actual data technical
Jul 02, 2005 Re: Model selection criteria? technical
Jul 12, 2005 Re: Simulation vs. actual data technical
Jul 12, 2005 Re: Simulation vs. actual data technical
Jul 14, 2005 End of semester MCQ and short answer question technical
Jul 14, 2005 Re: Simulation vs. actual data technical
Jul 17, 2005 Re: End of semester MCQ and short answer question technical
Jul 17, 2005 Re: End of semester MCQ and short answer question technical
Jul 17, 2005 Re: End of semester MCQ and short answer question technical
Jul 21, 2005 Subject: Re: Failing table step upon redefining ETAs as additive (or high correlations in $COV output) technical
Aug 26, 2005 Re: Installation error message. technical
Aug 26, 2005 Using CONT data item technical
Aug 26, 2005 Re: Using CONT data item technical
Sep 01, 2005 Re: gcc and ADVAN5 -7 technical
Sep 01, 2005 Re: gcc and ADVAN5 -7 technical
Sep 30, 2005 Re: MM elimination vs dose technical
Oct 20, 2005 Re: Inclusion of covariates and model improvement technical
Dec 20, 2005 Re: PD modeling: What is the most efficient approach to transfer data? technical
Dec 20, 2005 Re: PD modeling: What is the most efficient approach to transfer data? technical
Feb 01, 2006 Re: 100% CPU with NONMEM technical
Feb 02, 2006 Re: Where to download Population Fisher Information Matrix? technical
Mar 29, 2006 Re: GAM analysis and further action technical
Apr 27, 2006 Re: Placebo in indirect PD models technical
Jul 04, 2006 Re: likelihood model for missing SEX data technical
Jul 05, 2006 Re: likelihood model for missing SEX data technical
Jul 07, 2006 Re: likelihood model for missing SEX data technical
Jul 30, 2006 Re: Problems with an apparent compiler-senstive model technical
Jul 30, 2006 Re: Problems with an apparent compiler-senstive model technical
Aug 01, 2006 Re: Problems with an apparent compiler-senstive model technical
Aug 02, 2006 Re: Problems with an apparent compiler-senstive model technical
Aug 03, 2006 Re: Problems with an apparent compiler-senstive model technical
Aug 03, 2006 Re: Problems with an apparent compiler-senstive model technical
Aug 08, 2006 Re: How could I determine which thetan(n=1,2,3...) will be put to K or CL? technical
Aug 27, 2006 RE: Can we increase maximum number of function evaluations? technical
Sep 14, 2006 Re: NONMEM technical
Sep 22, 2006 Re: Bootstrap question technical
Sep 25, 2006 RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION technical
Sep 25, 2006 Re: Bootstrap question technical
Sep 25, 2006 Re: Bootstrap question technical
Oct 01, 2006 RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION technical
Oct 02, 2006 RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION technical
Oct 02, 2006 Re: WRES AND OUTLIER IDENTIFICATION/EXCLUSION technical
Oct 05, 2006 Re: Some basic modeling results technical
Nov 12, 2006 Re: Help on rounding error ( error=134) ! technical
Nov 29, 2006 Welcome to the new small sample size world of NONMEM VI technical
Nov 30, 2006 Wings for NONMEM Version 600 for NONMEM VI news
Nov 30, 2006 MAXIDS=10000 technical
Nov 30, 2006 RE: Welcome to the new small sample size world of NONMEM VI technical
Dec 01, 2006 Re: MAXIDS=10000 technical
Dec 02, 2006 Pediatric Collaborators Sought job
Feb 02, 2007 Re: compiler option issue technical
Feb 07, 2007 Re: Pred Exit Error =1 with $SIM technical
Feb 16, 2007 Re: Intra-species PK scaling from adults toinfantsfor antibody drugs technical
Feb 26, 2007 Re: WARNING 48 technical
Feb 28, 2007 Re: create simulation file for 5000 patients ? technical
Mar 04, 2007 Re: parent drug and metabolite technical
Mar 05, 2007 Re: parent drug and metabolite technical
Mar 07, 2007 Wings for NONMEM Version 611 news
Mar 08, 2007 Re: change from mass to molar units technical
Mar 19, 2007 Re: General question on modeling technical
Mar 20, 2007 Re: General question on modeling technical
Mar 24, 2007 Outcome based evidence for merits of TCI/TDM technical
Mar 25, 2007 Re: Outcome based evidence for merits of TCI/TDM technical
Mar 27, 2007 Re: AUC and segmented post treatment exposure technical
Mar 27, 2007 Re: Outcome based evidence for merits of TCI/TDM (fwd) technical
Apr 11, 2007 Re: Weibull distribution technical
Apr 11, 2007 Re: Bayesian estimation example technical
Apr 27, 2007 Re: modeling the circadian baseline technical
May 27, 2007 Re: NONMEM ODE solver technical
Jul 03, 2007 Re: COX Proportional Hazard Model with Time Dependent Covariate technical
Jul 03, 2007 Re: COX Proportional Hazard Model with Time DependentCovariate technical
Jul 05, 2007 Re: COX Proportional Hazard Model with Time DependentCovariate Nick Holford technical
Jul 19, 2007 Re: Running NMV with Intel 9 from S+ technical
Jul 19, 2007 Re: Simultaneous PK and Cell Life Span PD modeling technical
Jul 20, 2007 Re: Minimization terminated ? technical
Jul 21, 2007 Re: Minimization terminated ? technical
Jul 24, 2007 Re: Nonparametric method technical
Jul 25, 2007 American Conference on Pharmacometrics - Sponsorship event
Jul 26, 2007 Re: Peritoneal Dialysis Data preparation technical
Jul 30, 2007 $MIX and $CONTR technical
Jul 31, 2007 Re: $MIX and $CONTR technical
Aug 15, 2007 Re: Model Comparison and Viewing of Output technical
Aug 22, 2007 Re: Assigning occasions to sparse data technical
Aug 22, 2007 Re: unidentifiable model technical
Aug 23, 2007 Re: Assigning occasions to sparse data technical
Sep 11, 2007 WFN Version 612/410, NMQ4WFN, R for NONMEM news
Sep 13, 2007 S-plus multivariate normal distribution technical
Sep 14, 2007 Re: S-plus multivariate normal distribution technical
Sep 27, 2007 bug/feature in $AES technical
Sep 28, 2007 Re: bug/feature in $AES technical
Oct 01, 2007 Re: bug/feature in $AES technical
Oct 05, 2007 Re: Error model - Insider trading problem technical
Oct 11, 2007 Re: Modeling compartment initial conditinns using ETA()= EPS(1) and CPZEROmeasure technical
Oct 22, 2007 Re: Automated way to extract NM output technical
Oct 25, 2007 Re: Reporting Modeling Results technical
Oct 26, 2007 Re: Reporting Modeling Results technical
Oct 27, 2007 Re: Reporting Modeling Results technical
Nov 06, 2007 Re: NMUsers - chm version technical
Nov 28, 2007 Re: help with indirect reponse model technical
Dec 03, 2007 Re: How to increase total image size in Fortran? technical
Feb 10, 2008 Re: g77 compiler technical
Feb 20, 2008 Re: Using Prior subroutine technical
Feb 20, 2008 Re: PRIOR SUBROUTINE technical
Feb 27, 2008 Re: System call from R causes loss of cursor control technical
Mar 05, 2008 Re: Missing time data technical
Mar 26, 2008 Re: Re: [NMUSERS] Questions on fitting pediatric PK data using NONMEM technical
Apr 16, 2008 Re: Non-influential Eta technical
Apr 22, 2008 Re: truncation & simulation technical
Apr 23, 2008 Pop PK of Atenolol technical
May 23, 2008 Re: Visual predictive check! technical
May 25, 2008 Re: Visual predictive check! technical
May 28, 2008 Re: Sparse (pediatric) and rich (adult) data technical
May 29, 2008 Re: Sparse (pediatric) and rich (adult) data technical
Jun 06, 2008 Re: 95% prediction interval and $OMEGA technical
Jul 03, 2008 Re: Estimation of standard error technical
Jul 12, 2008 Re: Michaelis-Menten model technical
Jul 14, 2008 Re: Your suggestions/thoughts needed on allometric base or final model technical
Jul 14, 2008 Re: Your suggestions/thoughts needed on allometric base or final model technical
Jul 15, 2008 Re: Your suggestions/thoughts needed on allometric base or final model technical
Jul 15, 2008 Re: Your suggestions/thoughts needed on allometric base or final model technical
Jul 17, 2008 Re: Build a cell-cycle based tumor growth model technical
Jul 19, 2008 Re: cyst size modeling technical
Jul 20, 2008 Re: cyst size modeling technical
Jul 22, 2008 Re: PPC technical
Jul 23, 2008 Re: FW: PPC technical
Jul 24, 2008 Re: FW: PPC technical
Jul 25, 2008 Re: FW: PPC technical
Jul 26, 2008 Re: FW: PPC technical
Jul 30, 2008 Re: FW: PPC technical
Jul 31, 2008 Re: FW: PPC technical
Aug 01, 2008 Re: PPC technical
Aug 14, 2008 Re: Categorical covariates technical
Aug 19, 2008 Re: NONMEM VI 2.0 Bug Alert #1 technical
Aug 21, 2008 Re: Any solutions to both "minimization terminated" and "high" relative bioavailability technical
Aug 21, 2008 Re: Any solutions to both "minimization terminated" and "high" relative bioavailability technical
Aug 26, 2008 Re: How to scale PARAMETERs technical
Sep 02, 2008 Re: unbalanced design technical
Sep 03, 2008 Re: compiler selection technical
Sep 08, 2008 Re: NONMEM memory vs. run time technical
Sep 12, 2008 Re: modeling binary observations technical
Sep 13, 2008 Re: modeling binary observations technical
Sep 17, 2008 Re: FW: Revisit parameterization question technical
Sep 19, 2008 Re: Metabolite inhibition model technical
Sep 19, 2008 Re: Scaling for pediatric study planning technical
Sep 20, 2008 Re: Scaling for pediatric study planning technical
Sep 21, 2008 Re: Scaling for pediatric study planning technical
Sep 24, 2008 Re: dataset codification technical
Oct 14, 2008 Re: How $simulation work with $estimation technical
Oct 15, 2008 Re: How $simulation work with $estimation technical
Oct 16, 2008 Re: Why population PK approach is good for pooling data compared to Classical statistical analysis? technical
Oct 16, 2008 Re: Why population PK approach is good for pooling data compared to Classical statistical analysis? technical
Oct 16, 2008 Re: More Levels of Random Effects technical
Oct 16, 2008 Re: How $simulation work with $estimation technical
Oct 17, 2008 Re: More Levels of Random Effects technical
Oct 20, 2008 Re: More Levels of Random Effects technical
Oct 21, 2008 Re: Validation Strategy for NONMEM technical
Oct 23, 2008 Re: Quantitative criteria for the use of interoccasional variability (IOV) ? technical
Oct 23, 2008 Re: Quantitative criteria for the use of interoccasional variability (IOV) ? technical
Nov 05, 2008 Pharmacokinetics is what the body does to the drug ... technical
Nov 08, 2008 Re: Pharmacokinetics is what the body does to the drug ... technical
Nov 12, 2008 Re: NONMEM message technical
Nov 13, 2008 Re: NONMEM message technical
Nov 13, 2008 Re: Very small P-Value for ETABAR technical
Nov 14, 2008 Re: Very small P-Value for ETABAR technical
Nov 17, 2008 Re: Very small P-Value for ETABAR technical
Nov 17, 2008 Re: NONMEM and g77 technical
Nov 18, 2008 Re: NONMEM and g77 technical
Nov 18, 2008 Re: Models that abort before convergence technical
Nov 20, 2008 Re: Models that abort before convergence Addendum technical
Nov 20, 2008 The Wisdom of Lewis Sheiner technical
Nov 20, 2008 Re: Models that abort before convergence technical
Nov 21, 2008 Re: Models that abort before convergence technical
Nov 21, 2008 Re: Models that abort before convergence Addendum technical
Dec 09, 2008 Re: Simultaneous vs sequential for modeling parent AND metabolites in pop PK technical
Dec 09, 2008 Re: FO vs FOCE technical
Dec 09, 2008 Re: Simultaneous vs sequential for modeling parent AND metabolites in pop PK technical
Dec 09, 2008 Re: FO vs FOCE, sequential vs simultaneous technical
Dec 10, 2008 Re: Simultaneous vs sequential for modeling parent AND metabolites in pop PK technical
Dec 10, 2008 Re: Simultaneous vs sequential for modeling parent AND metabolites in pop PK technical
Dec 11, 2008 Re: Simultaneous vs sequential for modeling parent AND metabolites in pop PK technical
Dec 12, 2008 Re: ETA on ALAG1 technical
Jan 07, 2009 Announcement: Sheiner Rowland Advanced Course in PKPD - Washington DC 3-8 March 2009 event
Jan 07, 2009 Announcement: Sheiner Rowland Advanced Course in PKPD - Washington DC 3-8 May 2009 [Corrected] event
Jan 07, 2009 Announcement: Sheiner Rowland Advanced Course in PKPD - Washington DC 3-8 March 2009 event
Jan 07, 2009 Announcement: Sheiner Rowland Advanced Course in PKPD - Washington DC 3-8 May 2009 [Corrected] event
Jan 08, 2009 Re: Announcement: Sheiner Rowland Advanced Course in PKPD - Washington DC 3-8 May 2009 [Corrected] event
Jan 08, 2009 Re: Announcement: Sheiner Rowland Advanced Course in PKPD - Washington DC 3-8 May 2009 [Corrected] event
Jan 12, 2009 Re: CrcL or Cr in pediatric model technical
Jan 13, 2009 Re: CrcL or Cr in pediatric model technical
Feb 06, 2009 Re: simulation question technical
Feb 09, 2009 Sheiner/Rowland Advanced PKPD Course Washington DC May 3-8 2009 event
Feb 10, 2009 Sheiner/Rowland Advanced PKPD Course Washington DC May 3-8 2009 event
Mar 16, 2009 Re: 20 variable limit in $INPUT technical
Mar 22, 2009 Re: calculation of AUC technical
Mar 22, 2009 Re: Proposal to built an interface for SADAPT technical
Mar 24, 2009 Re: Proposal to built an interface for SADAPT technical
Mar 24, 2009 Re: calculation of AUC technical
Apr 01, 2009 Re: Schwartz formulae technical
Apr 02, 2009 Re: Schwartz formulae technical
Apr 10, 2009 Re: When is F1 Evaluated technical
Apr 13, 2009 Re: Imaginary concentrations technical
Apr 14, 2009 Re: VPC with Mixture Model technical
Apr 15, 2009 Re: VPC with Mixture Model technical
Apr 15, 2009 Re: OMEGA BLOCK with mixture model? technical
Apr 15, 2009 Re: OMEGA selection technical
Apr 16, 2009 Re: OMEGA BLOCK with mixture model? technical
Apr 17, 2009 Re: OMEGA BLOCK with mixture model? technical
Apr 21, 2009 Re: Bootstrap analysis technical
Apr 23, 2009 Re: PharmPK Re: NMTRAN error technical
Apr 23, 2009 Re: Resetting af single compartment technical
Jun 02, 2009 Re: Problems with IGNORE technical
Jun 02, 2009 Wings for NONMEM version 700 (beta support for NONMEM 7 beta) news
Jun 09, 2009 Re: Time to event analysis using NONMEM technical
Jul 04, 2009 Re: NONMEM 7 Update technical
Jul 08, 2009 Re: Simulations with/without residual error technical
Jul 08, 2009 Re: OMEGA off-diagonal elements parameterized as correlations technical
Jul 09, 2009 Re: AW: Simulations with/without residual error technical
Jul 10, 2009 Re: AW: Simulations with/without residual error technical
Jul 10, 2009 Re: OMEGA off-diagonal elements parameterized as correlations technical
Jul 11, 2009 Re: OMEGA off-diagonal elements parameterized as correlations technical
Jul 17, 2009 Re: covariance step technical
Jul 21, 2009 Re: Modeling of two time-to-event outcomes technical
Jul 22, 2009 Re: Modeling of two time-to-event outcomes technical
Jul 23, 2009 Re: Modeling of two time-to-event outcomes technical
Jul 24, 2009 Re: Modeling of two time-to-event outcomes technical
Jul 26, 2009 Re: AW: Simulations with/without residual error technical
Jul 27, 2009 Re: AW: Simulations with/without residual error technical
Aug 05, 2009 Re: Steady state model technical
Aug 06, 2009 Re: count simulations technical
Aug 07, 2009 Re: Re: count simulations technical
Aug 07, 2009 Re: Code to avoid flip-flop kinetics technical
Aug 10, 2009 Re: Re: count simulations technical
Aug 21, 2009 Re: Linear VS LTBS technical
Aug 23, 2009 Re: Linear VS LTBS technical
Aug 24, 2009 Re: Linear VS LTBS technical
Aug 24, 2009 What does convergence/covariance show? technical
Aug 24, 2009 Honest measurements technical
Aug 25, 2009 Re: What does convergence/covariance show? technical
Aug 26, 2009 Re: What does convergence/covariance show? technical
Aug 27, 2009 Re: PK data from individuals who vomited after drug ingestion technical
Aug 27, 2009 Re: Avoid scientific notation in tables technical
Aug 27, 2009 Re: What does convergence/covariance show? technical
Aug 28, 2009 Re: What does convergence/covariance show? technical
Sep 18, 2009 Re: VPC appropriateness in complex PK technical
Sep 19, 2009 WFN for NONMEM 7 news
Sep 20, 2009 WFN for NONMEM 7 news
Sep 21, 2009 Re: VPC appropriateness in complex PK technical
Sep 22, 2009 Re: VPC appropriateness in complex PK technical
Sep 22, 2009 Re: time-dependent residual error models technical
Sep 24, 2009 Re: time-dependent residual error models technical
Sep 24, 2009 Re: PARAMETER ESTIMATE IS NEAR ITS BOUNDARY with NONMEM v6 technical
Sep 24, 2009 Re: PARAMETER ESTIMATE IS NEAR ITS BOUNDARY with NONMEM v6 technical
Sep 29, 2009 Re: time-dependent residual error models technical
Sep 30, 2009 Re: time-dependent residual error models technical
Oct 02, 2009 Re: multiple problems in a control file technical
Oct 02, 2009 Re: time-dependent residual error models technical
Oct 08, 2009 Re: Missing value when modeling categorical data technical
Oct 09, 2009 Re: Missing value when modeling categorical data technical
Oct 09, 2009 Re: time-dependent residual error models technical
Oct 10, 2009 Re: time-dependent residual error models technical
Oct 16, 2009 Re: The system cannot execute the specified program technical
Oct 17, 2009 Re: The system cannot execute the specified program technical
Oct 18, 2009 Re: The system cannot execute the specified program technical
Oct 19, 2009 Re: The system cannot execute the specified program technical
Oct 30, 2009 Re: NM7 Question on METHOD=IMP technical
Nov 01, 2009 Re: advan8 vs. advan13 technical
Nov 02, 2009 Re: advan8 vs. advan13 technical
Nov 04, 2009 Re: advan8 vs. advan13 (CORRECTION) technical
Nov 05, 2009 Re: advan8 vs. advan13 (CORRECTION) technical
Nov 05, 2009 Re: The system cannot execute the specified program technical
Nov 11, 2009 Sheiner-Rowland Advanced Course in PKPD -- Come and join in the fun! event
Nov 25, 2009 Re: NMUSERS-modeling dose and response technical
Dec 04, 2009 Re: Model building technical
Dec 05, 2009 Re: Model building technical
Dec 15, 2009 Re: Age effect on Clearance technical
Dec 21, 2009 Re: BSV and BOV interaction technical
Jan 20, 2010 Re: missing table file technical
Jan 21, 2010 Re: missing table file technical
Feb 13, 2010 WFN for NONMEM 7 - version 702 news
Mar 04, 2010 Re: Meta-analysis with Nonmem technical
Mar 28, 2010 Re: Parallel first order and Michaelis-Menten elimination technical
Mar 30, 2010 Re: Parallel first order and Michaelis-Menten elimination technical
Apr 06, 2010 Re: Generating Cmax at end of infusion technical
Apr 09, 2010 Correct NONMEM 7 reference technical
May 28, 2010 Re: distribution assumption of Eta in NONMEM technical
May 29, 2010 Re: distribution assumption of Eta in NONMEM technical
May 30, 2010 Re: distribution assumption of Eta in NONMEM technical
May 31, 2010 Re: distribution assumption of Eta in NONMEM technical
Jun 18, 2010 Re: Unexpected influence of parameter order on estimation results technical
Jun 18, 2010 Re: help on a minimization problem technical
Jun 23, 2010 WFN for NONMEM 7 - version 703 news
Jun 24, 2010 Re: simultaneous PK/PD technical
Jun 29, 2010 Re: g77 Problem technical
Aug 05, 2010 Re: ETA1 tending to zero in a simple model technical
Sep 07, 2010 Re: How serious are negative eigenvalues? technical
Sep 14, 2010 Re: is there a way to change fit to csv technical
Oct 05, 2010 PAGANZ 2011 Feb 7-9 Auckland New Zealand -- Full Registration is now Open event
Oct 11, 2010 Academic Clinical Pharmacologist Wanted at the University of Auckland job
Oct 23, 2010 Re: New versus old NONMEM technical
Oct 26, 2010 Re: New versus old NONMEM technical
Oct 29, 2010 Re: Hessian of posterior density is non positive definite during search technical
Oct 31, 2010 Re: Rational of using IOV technical
Nov 01, 2010 Re: Rational of using IOV technical
Nov 20, 2010 What does "Second Error signal from LINV1PD: 129" mean? technical
Dec 10, 2010 Re: question about disease progress and drop out joint model technical
Dec 13, 2010 Re: question about simulation based on joint disease progress and dropout model technical
Jan 04, 2011 Re: MS Visual Studio Express technical
Jan 16, 2011 Re: Mixture model for Disease Progression technical
Jan 24, 2011 Re: error message technical
Feb 03, 2011 Re: Inclusion of Analytical Expressions in NONMEM control file technical
Feb 03, 2011 Re: Inclusion of Analytical Expressions in NONMEM control file technical
Feb 17, 2011 Re: Growth Curve Modelling technical
Feb 24, 2011 Re: Growth Curve Modelling technical
Mar 01, 2011 Re: [Fwd: occasions during pregnancy] technical
Mar 14, 2011 Re: How to generate a random number with $EST technical
Mar 15, 2011 Re: coding for sequential NM-runs technical
Mar 18, 2011 Re: initials for autocovariate technical
Mar 21, 2011 Re: repetitive parameter estimation technical
Mar 24, 2011 Re: Time-to-event analysis with $DES technical
Mar 28, 2011 Re: Time-to-event analysis with $DES technical
Mar 31, 2011 Re: basic questions... technical
Apr 07, 2011 University of Cape Town Research Officer for Pharmacometrics technical
Apr 25, 2011 Re: Replacement of values during simulation technical
May 16, 2011 Re: protein binding model technical
May 18, 2011 Re: Table formatting in NONMEM7- can I skip the "Table No." header row? technical
May 21, 2011 Re: Simple parallel benchmark for Nonmem 7.2 with large Bayes problem technical
May 24, 2011 Re: MPI installation on Win 7/ 64 bit technical
May 27, 2011 Re: WFN with NONMEM 7.2.0 news
May 30, 2011 WFN for NONMEM 7.2.0 - version 720 news
Jun 02, 2011 Re: Question regarding Calculation Process in $DES BLOCK technical
Jun 02, 2011 Re: MPI error when run directory is a Windows network drive technical
Jun 02, 2011 WFN for NONMEM 7.2.0 - version 720 news
Jun 03, 2011 Re: PAMAM-OH nanoparticles technical
Jun 16, 2011 Re: Re: MPI error when run directory is a Windows network drive technical
Jun 17, 2011 Re: Re: MPI error when run directory is a Windows network drive technical
Jun 17, 2011 Re: Re: MPI error when run directory is a Windows network drive technical
Jul 01, 2011 Re: CCV or Additive error models? technical
Jul 04, 2011 Re: CCV or Additive error models? technical
Jul 09, 2011 Re: Confidence intervals of PsN bootstrap output technical
Jul 11, 2011 Re: Confidence intervals of PsN bootstrap output technical
Jul 21, 2011 Re: Modeling Hemodialysis clearance technical
Jul 28, 2011 Re: Time to event analysis technical
Aug 01, 2011 The Sheiner/Rowland advanced PK-PD course in Singapore 12-17 February 2012 event
Aug 03, 2011 Re: allometric scaling for renal elimination drug technical
Aug 14, 2011 The Sheiner/Rowland advanced PK-PD course in Singapore 12-17 February 2012 - IMPORTANT Update event
Aug 15, 2011 Re: Time to Event Model technical
Aug 19, 2011 Re: flexible infusion rate model technical
Aug 20, 2011 Re: flexible infusion rate model technical
Aug 23, 2011 SETUP72 on linux system -- why does gfortran give these compile errors? technical
Sep 02, 2011 Re: Parent and metabolite model-residual error model and L2 technical
Sep 22, 2011 Re: "ERROR IN LSODA: CODE -1" technical
Sep 23, 2011 Re: "ERROR IN LSODA: CODE -1" technical
Sep 23, 2011 The Sheiner/Rowland advanced PK-PD course in Singapore 12-17 February 2012 - Time is running out... event
Sep 24, 2011 The Sheiner/Rowland advanced PK-PD course in Singapore 12-17 February 2012 - Time is running out... event
Oct 14, 2011 Re: PRIOR method without covariance matrix of estimates? technical
Oct 17, 2011 Re: alt on Q in 2 compartment model technical
Oct 17, 2011 Re: Steady state dose technical
Oct 18, 2011 Re: help on problem with baseline estimation technical
Nov 03, 2011 Re: CycleCloud BigScience Challenge giving away ~8-hours on 30000 core cluster for research technical
Nov 11, 2011 Re: Sequential PD model parameter stays at initial estimation problem technical
Nov 23, 2011 The Sheiner/Rowland advanced PK-PD course in Singapore 12-17 February 2012 -- Last chance for Earl Bird registration event
Nov 30, 2011 Re: Request for Assistance - Problems with Posting technical
Dec 01, 2011 2 Day Workshop on Basic Pharmacokinetics and Pharmacodynamics,Canberra, Australia,9th & 10th February 2012 event
Dec 02, 2011 2 Day Workshop on Basic Pharmacokinetics and Pharmacodynamics,Canberra, Australia,9th & 10th February 2012 event
Dec 13, 2011 Re: Different assays for different studies technical
Dec 13, 2011 Re: 202 Fortran Syntax of wings for NM7 technical
Jan 09, 2012 Re: How to set CMT value for 2-compartment bacterial model technical
Jan 10, 2012 Re: VPC for non-uniform sampling technical
Jan 12, 2012 Re: consistent error in control stream technical
Jan 30, 2012 Re: Intel fortran compiler 12 and Wings for NONMEM news
Feb 01, 2012 Re: PK/PD modeling - fixing population paramterers vs. fixing both pop. and individual parameters technical
Feb 01, 2012 Re: PK/PD modeling - fixing population paramterers vs. fixing both pop. and individual parameters technical
Feb 04, 2012 Re: medians of the simulation in VPC are systematically below the medians of the observations when the model fit looks fine. technical
Feb 20, 2012 Re: Sensitive analysis technical
Mar 21, 2012 Re: Mixed Models technical
Apr 19, 2012 Re: FDATA technical
May 05, 2012 Re: mixture model coding technical
May 19, 2012 Re: saturable metabolism of 5FU technical
May 21, 2012 Re: VD as a fraction of another VD technical
May 22, 2012 Re: VD as a fraction of another VD technical
May 24, 2012 Re: Successful minimization and covariance technical
Jun 13, 2012 Re: omega matrix - friendly suggestion technical
Jun 14, 2012 Open PhD and postdoc positions at INRIA, Grenoble, France (DDMoRe consortium) for October 2012 job
Jul 11, 2012 Re: Question about interoccation variability technical
Jul 12, 2012 Re: Question about interoccation variability technical
Jul 25, 2012 Re: A question about TOL technical
Jul 26, 2012 International Society of Pharmacometrics technical
Aug 08, 2012 Re: Plasma and Urine data technical
Aug 12, 2012 Re: Intel vs AMD technical
Aug 13, 2012 Re: Intel vs AMD technical
Aug 14, 2012 Re: restart NONMEM technical
Aug 15, 2012 Re: restart NONMEM technical
Aug 26, 2012 2 Day Introductory Workshop on Pharmacokinetics and Pharmacodynamics,Canberra, Australia, 4th & 5th December 2012 event
Aug 26, 2012 2 Day Introductory Workshop on NONMEM, Canberra, Australia, 6th & 7th December 2012 event
Aug 26, 2012 2 Day Introductory Workshop on Pharmacokinetics and Pharmacodynamics,Canberra, Australia, 4th & 5th December 2012 event
Sep 16, 2012 Grid licensing of NONMEM technical
Sep 28, 2012 MPI on linux Exit status=1 technical
Sep 29, 2012 Re: MPI on linux Exit status=1 technical
Oct 13, 2012 What does MU_WARNING 24 mean? technical
Oct 27, 2012 Re: WFN problem news
Nov 07, 2012 Re: RE: Proper way to handle the pre-first dose PK observation for non-endogenous drug technical
Nov 08, 2012 Re: RE: Proper way to handle the pre-first dose PK observation for non-endogenous drug technical
Dec 09, 2012 Re: modelling strategy question technical
Dec 23, 2012 Re: NMusers: Population PK model dose in mg/m2 technical
Jan 09, 2013 Re: Minimisation problem... technical
Jan 25, 2013 Mixture model simulation technical
Jan 29, 2013 Re: RANDOM VARIABLE IS DEFINED IN A NESTED IF STRUCTURE technical
Feb 12, 2013 Re: Additive residual error technical
Feb 18, 2013 Re: RE: Simulation settgin in the precence of Shrinkage in PK when doing PK-PD analysis technical
Feb 19, 2013 Re: RE: Simulation settgin in the precence of Shrinkage in PK when doing PK-PD analysis technical
Feb 21, 2013 Re: RE: Simulation settgin in the precence of Shrinkage in PK when doing PK-PD analysis technical
Mar 07, 2013 Re: M3 method and multiple LOQ values technical
Mar 19, 2013 Re: use of REPEAT option technical
Apr 04, 2013 Re: seeking help on NONMEM code for simulation of Repeated Time to Event Data technical
Apr 24, 2013 Re: AW: Right skewness in bootstrap distribution technical
May 23, 2013 Sheiner Rowland Advanced PKPD Course 9-13 Sept 2013, Tokyo, Japan event
Jul 08, 2013 Re: simulation with uncertainty of THETA technical
Jul 13, 2013 Re: Covariance matrix of parameter estimates (standard errors) technical
Jul 14, 2013 Re: Covariance matrix of parameter estimates (standard errors) technical
Jul 25, 2013 Re: if-the-statement for 3 class categorical covariate technical
Aug 10, 2013 Re: Access to iteration number if $PK or $PRED technical
Aug 23, 2013 Re: Time-varing covariate technical
Aug 26, 2013 Renal function as a covariate technical
Aug 27, 2013 Re: Renal function as a covariate technical
Aug 28, 2013 Re: Time-varing covariate technical
Sep 02, 2013 WCoP 2016! Request for initial expression of interest to host event
Sep 02, 2013 Re: Time-varing covariate and renal function as a covariate technical
Sep 04, 2013 Re: Time-varing covariate and renal function as a covariate technical
Sep 07, 2013 Re: Time-varing covariate and renal function as a covariate technical
Sep 20, 2013 Re: AW: Re: Parameter Estimation in IF Conditioning Statement technical
Oct 08, 2013 Re: Change of NSIG or R matrix technical
Oct 22, 2013 Re: Change of NSIG or R matrix technical
Oct 23, 2013 Re: Change of NSIG or R matrix technical
Oct 27, 2013 Re: question about sampling time technical
Nov 09, 2013 Re: Reporting and handling values below the limit of quantification technical
Nov 11, 2013 Re: Reporting and handling values below the limit of quantification technical
Nov 12, 2013 Re: Reporting and handling values below the limit of quantification technical
Nov 25, 2013 Re: Getting rid of correlation issues between CL and volume parameters technical
Dec 09, 2013 WFN for NONMEM 7.3.0 - version 731 news
Dec 10, 2013 Re: Transit Absorption Model in NONMEM technical
Jan 17, 2014 Re: backward integration from t-a to t technical
Jan 18, 2014 Re: backward integration from t-a to t technical
Mar 26, 2014 Re: call random: 372 "R" IN CALL RANDOM MAY NOT BE USED GLOBALLY IN ANOTHER BLOCK. technical
Mar 27, 2014 Re: call random: 372 "R" IN CALL RANDOM MAY NOT BE USED GLOBALLY IN ANOTHER BLOCK. technical
Mar 29, 2014 Re: NONMEM vs SPSS technical
Mar 30, 2014 Re: Fatal error: NM7.30+WFN news
May 01, 2014 WCoP 2016: World Conference on Pharmacometrics August 21-24 Brisbane Australia event
Sep 04, 2014 Re: Inflated random effects showed by VPC technical
Sep 30, 2014 Re: OMEGA matrix technical
Oct 01, 2014 Why are my posts not appearing on nmusers? technical
Oct 01, 2014 Re: OMEGA matrix technical
Oct 03, 2014 Re: Negative DV values technical
Oct 04, 2014 WFN for NONMEM 7.3.0 - version 735 news
Nov 20, 2014 Re: A question about handling large-scale data technical
Jan 16, 2015 Re: RE: IIV on res error technical
Feb 12, 2015 Re: RE: Standard errors of estimates for strictly positive parameters technical
Feb 12, 2015 Re: RE: Standard errors of estimates for strictly positive parameters technical
Mar 10, 2015 Applied Pharmacokinetics and Pharmacodynamics and Population Analysis with NONMEM. Santiago, Chile Aug 31-Sep 4 2015 technical
Mar 10, 2015 Applied Pharmacokinetics and Pharmacodynamics and Population Analysis with NONMEM. Santiago, Chile Aug 31-Sep 4 2015 technical
Jun 12, 2015 Re: Population PKPD using hair drug concentration technical
Jun 18, 2015 Re: $SIZES failed technical
Jul 09, 2015 Re: How to account for M-M in the presence of Ka>Ke constraint in PopPK model technical
Jul 09, 2015 Re: How to account for M-M in the presence of Ka>Ke constraint in PopPK model technical
Oct 06, 2015 Re: [FORGED] Phsysiological model technical
Oct 09, 2015 World Conference on Pharmacometrics 2016 - Registration and Call for papers event
Oct 09, 2015 World Conference on Pharmacometrics 2016 - Registration and Call for papers event
Oct 22, 2015 Re: Saving solution to differential equation from previous time point and carry over to next time point technical
Oct 22, 2015 Re: Saving solution to differential equation from previous time point and carry over to next time point technical
Nov 16, 2015 Re: RE: Pediatric brain scaling technical
Nov 19, 2015 Re: Incorporating standard deviation (SD) on fitted mean values technical
Nov 19, 2015 Re: Incorporating standard deviation (SD) on fitted mean values technical
Nov 20, 2015 Re: PRED for BLQ-like observations technical
Dec 09, 2015 Re: RE: Weight based dosing technical
Dec 19, 2015 Sheiner Rowland Advanced Course in PKPD Sils Maria 2016,Sunday April 3 through Friday April 8 - Early Bird Registration event
Dec 19, 2015 WCoP 2016 -- World Conference on Pharmacometrics 21-24 August 2016, Brisbane, Australia event
Dec 19, 2015 Sheiner Rowland Advanced Course in PKPD Sils Maria 2016,Sunday April 3 through Friday April 8 - Early Bird Registration event
Dec 19, 2015 WCoP 2016 -- World Conference on Pharmacometrics 21-24 August 2016, Brisbane, Australia event
Jan 06, 2016 Re: unbalanced data set technical
Jan 21, 2016 Re: NONMEM code verification technical
Feb 15, 2016 World Conference on Pharmacometrics 2016 - ORAL submission closing date is Monday 7 March 2016 event
Feb 15, 2016 World Conference on Pharmacometrics 2016 - ORAL submission closing date is Monday 7 March 2016 event
Feb 16, 2016 World Conference on Pharmacometrics 2016 - ORAL submission closing date is Monday 7 March 2016 event
Feb 16, 2016 World Conference on Pharmacometrics 2016 - ORAL submission closing date is Monday 7 March 2016 event
Mar 04, 2016 World Conference on Pharmacometrics 2016 - ORAL submission closing date is Monday 7 March 2016 (your local time) event
Mar 04, 2016 World Conference on Pharmacometrics 2016 - ORAL submission closing date is Monday 7 March 2016 (your local time) event
Apr 06, 2016 Re: ASCO and pharmacometrics technical
Apr 13, 2016 WCoP 2016 Registration and Final Call for Abstracts event
Apr 23, 2016 Re: Time varying volume of distribution implementation technical
Apr 25, 2016 Re: Rounding (error=134) or obj. func. is infinite (error=136) technical
Apr 25, 2016 Re: Rounding (error=134) or obj. func. is infinite (error=136) technical
Apr 30, 2016 Academic Position for a Pharmacometrician - Lecturer/Senior Lecturer position in Auckland job
Apr 30, 2016 Academic Position for a Pharmacometrician - Lecturer/Senior Lecturer position in Auckland job
May 23, 2016 Understanding allometry technical
May 24, 2016 WCoP 2016 Brisbane Aug 21-24 - Early Bird Registration Closes in 3 weeks (15 June) event
May 24, 2016 WCoP 2016 Brisbane Aug 21-24 - Early Bird Registration Closes in 3 weeks (15 June) event
May 29, 2016 Re: Understanding allometry technical
Jun 01, 2016 Understanding allometry technical
Jun 07, 2016 WCoP 2016 - Final reminder - early bird registration closes in one week - Wednesday 15 June event
Jun 07, 2016 WCoP 2016 - Final reminder - early bird registration closes in one week - Wednesday 15 June event
Sep 02, 2016 Re: Simultaneous pk model of 2 drugs technical
Dec 19, 2016 Re: AW: $Error log transformed technical
Jan 16, 2017 Re: Objective function technical
Mar 09, 2017 Re: [FORGED] RE: question about random seed for simulation technical
Mar 10, 2017 Re: [FORGED] RE: question about random seed for simulation technical
Apr 24, 2017 Re: [FORGED] Modelling IV and IP simultaneously technical
May 04, 2017 WFN for NONMEM 7.4.0 - version 742 news
May 16, 2017 Advanced PKPD: The Sheiner and Rowland Advanced Course in PKPD Lambertville 10-15 Sept 2017 event
May 16, 2017 Advanced PKPD: The Sheiner and Rowland Advanced Course in PKPD Lambertville 10-15 Sept 2017 event
Jun 14, 2017 Re: Inherit past calculation of parameter in NONMEM technical
Sep 17, 2017 Sheiner Rowland Advanced Course in PKPD Sils Maria 2018, Sunday April 8 through Friday April 13 - Early Bird Registration event
Sep 17, 2017 Sheiner Rowland Advanced Course in PKPD Sils Maria 2018, Sunday April 8 through Friday April 13 - Early Bird Registration event
Nov 21, 2017 Second ANNOUNCEMENT - The Sheiner-Rowland Advanced Course in PKPD - Melbourne, Australia 2018 event
Nov 21, 2017 Second ANNOUNCEMENT - The Sheiner-Rowland Advanced Course in PKPD - Melbourne, Australia 2018 event
Nov 28, 2017 Third ANNOUNCEMENT - The Sheiner-Rowland Advanced Course in PKPD - Melbourne, Australia 2018 event
Nov 28, 2017 Third ANNOUNCEMENT - The Sheiner-Rowland Advanced Course in PKPD - Melbourne, Australia 2018 event
Dec 06, 2017 Re: [FORGED] Allometric scaling of renal clearance with estimated glomerular filtration rate technical
Dec 06, 2017 Re: [FORGED] Allometric scaling of renal clearance with estimated glomerular filtration rate technical
Dec 07, 2017 Re: Allometric scaling of renal clearance with estimated glomerular filtration rate technical
Dec 07, 2017 Re: Allometric scaling of renal clearance with estimated glomerular filtration rate technical
Dec 20, 2017 Re: Numerical integreaion and change in clearance over time technical
Jan 24, 2018 Re: $ABBR REPLACE Limitations? technical
May 14, 2018 RE: Using Root-finding techniques to find Cmax/Tmax technical
May 14, 2018 Please help Winnie unsubscribe admin
Jun 04, 2018 RE: [Suggest] NONMEM adds UTF-8 support for csv files(B technical
Jun 04, 2018 RE: [Suggest] NONMEM adds UTF-8 support for csv files technical
Jun 14, 2018 RE: Context-free lexer for NM-TRAN technical
Sep 14, 2018 Come to PAGANZ 2019 in Auckland NZ - 6th-9th February event
Oct 04, 2018 Come to PAGANZ 2019 in Auckland NZ - 6th-9th February event
Nov 01, 2018 Send your abstract to PAGANZ 2019 in Auckland NZ - 6th-9th February event
Dec 07, 2018 Send your abstract to PAGANZ 2019 in Auckland NZ - 6th-9th February event
Jan 04, 2019 Send your abstract to PAGANZ 2019 in Auckland NZ - 6th-9th February - FINAL DAYS event
Jan 04, 2019 Send your abstract to PAGANZ 2019 in Auckland NZ - 6th-9th February - FINAL DAYS event
Feb 13, 2019 RE: OFV or Diagnostic Plot ?? Which one rules... technical
Mar 18, 2019 RE: VPCs confidence intervals? technical
Mar 19, 2019 RE: How to format output table as purely comma-separated file technical
Mar 19, 2019 RE: How to format output table as purely comma-separated file technical
Apr 19, 2019 RE: Using Microsoft MPI with NONMEM technical
May 11, 2019 RE: bootstrap technical
Sep 16, 2019 Sheiner-Rowland Advanced PKPD Course Sils-Maria 2020 Sunday March 29 through Friday April 3 event
Sep 16, 2019 Sheiner-Rowland Advanced PKPD Course Sils-Maria 2020 Sunday March 29 through Friday April 3 event
Nov 17, 2019 Advanced PKPD Course Sils-Maria 2020 Sunday March 29 through Friday April 3 event
Jan 06, 2020 Advanced PKPD Course Sils-Maria 2020 Sunday March 29 through Friday April 3 - Early Bird closing soon event
Feb 11, 2020 RE: [FORGED] $FINEDATA technical
Feb 14, 2020 RE: How to calculate confidence interval (CI) and prediction interval (PI) of individual prediction (IPRED) in NONMEM technical
Feb 21, 2020 Advanced PKPD Course Sils-Maria 2020 Sunday March 29 through Friday April 3 - Early bird extended to 28 March event
Feb 21, 2020 Advanced PKPD Course Sils-Maria 2020 Sunday March 29 through Friday April 3 - Early bird extended to 28 March event
Jun 02, 2020 RE: Negative concentration from simulation technical
Aug 12, 2020 RE: Random effect on ALAG between dose events technical
Mar 23, 2021 Wings for NONMEM version WFN750 for NONMEM 7.5.0 news
Apr 14, 2021 mpiexec exit code 1 even though NONMEM MPI run was successful technical
Apr 29, 2021 RE: Assessment of elimination half life of mAb technical
Sep 05, 2022 RE: data technical
Dec 20, 2022 RE: Off diagonals in $TABLE technical
Jul 06, 2023 RE: Specify full OMEGA matrix for simulation technical
Aug 18, 2023 RE: Observed (yaxis) vs Predicted (xaxis) Diagnostic Plot - Scientific basis. technical
May 11, 2024 RE: %RSE for IIV when expressed as %CV instead of variance technical
Jul 29, 2024 RE: Obtaining RSE% technical
Aug 03, 2024 RE: Sad news about Dr. Ludden news
Oct 09, 2024 RE: Emax model technical
Jan 12, 2025 RE: [EXTERNAL] Re: MU referencing and time-varying covariates technical
Jan 13, 2025 RE: [EXTERNAL] Re: MU referencing and time-varying covariates technical
May 24, 2025 Wings for NONMEM version 760 is now available news