Re: OMEGA HAS A NONZERO BLOCK

From:Nick Holford Subject:Re: [NMusers] OMEGA HAS A NONZERO BLOCK Date:Tue, 08 Oct 2002 10:20:22 +1300 Leonid, Leonid Gibiansky wrote: > > Shouldn't we agree that there are no absolute rules that fit all the cases? > That viewpoint might be called the Bayesian perspective. > I would put correlation to 1. Is there any reasons not to do it ? Please read my earlier "put up or shut up" response to Ken and Serge for my reasons why you should not do this. The priors against a correlation of 1 between CL and V are so strong that any data that pushed onto that boundary should be regarded with extreme suspicion. If you or anyone else can provide any theory to support the idea that CL and V could be perfectly correlated in reality then please tell me. Nick -- Nick Holford, Divn Pharmacology & Clinical Pharmacology University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand email:n.holford@auckland.ac.nz tel:+64(9)373-7599x6730 fax:373-7556 http://www.health.auckland.ac.nz/pharmacology/staff/nholford/