Re: posthoc step

From: "Nick Holford" n.holford@auckland.ac.nz Subject: Re: [NMusers] posthoc step Date: Thu, December 16, 2004 3:08 pm Tom, Thanks for the info on NONMEM's search methods. Base on this one example it looks like one should not be too concerned about initial estimates for the usual THETA/OMEGA/SIGMA search. It's a pity the ETA search is not so robust. Can you confirm that the ETA search method used during MAXEVAL=0 is the same as that used by METHOD=COND at each iteration? Nick -- Nick Holford, Dept Pharmacology & Clinical Pharmacology University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand email:n.holford@auckland.ac.nz tel:+64(9)373-7599x86730 fax:373-7556 http://www.health.auckland.ac.nz/pharmacology/staff/nholford/