Re: posthoc step

From: "Nick Holford" n.holford@auckland.ac.nz Subject: Re: [NMusers] posthoc step Date: Wed, December 15, 2004 1:47 am Steve, Let me ask the question more specifically -- if you used the same initial estimate for K that was used for NONMEM, SAS, Excel Solver i.e. 10, and fixed the residual error SD to 0.2 (no uncertainty!) with a prior on K of 10 and SD for the prior of 2 then what final estimate did you obtain? Did you get a number closer to 10 or closer to 1? Nick -- Nick Holford, Dept Pharmacology & Clinical Pharmacology University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand email:n.holford@auckland.ac.nz tel:+64(9)373-7599x86730 fax:373-7556 http://www.health.auckland.ac.nz/pharmacology/staff/nholford/