Pediatric Collaborators Sought

Hi, We are exploring maturation of aminoglycoside clearance with age in neonates/children and trying to disentangle development from size changes. In order to investigate maturation we would like to compile a large data set looking at renal function with age. We already have quite a lot of data describing aminoglycoside total clearance from which we have tried to deduce renal function but it would be much more satisfying to get some actual measurents of renal clearance -- creatinine, inulin, drugs -- and/or measurements of GFR. We have located a large data set in the literature but unfortunately the authors, though willing, are unable to find the numbers again. So we are starting over again and seeking help from anyone who would like to contribute their data, no matter who small the numbers, that would let us build (and keep building) a data set that can be used to describe the maturation of renal function as well as the changes with body size. If you are interested in helping us by adding your own data to a pool we would be very grateful if you would contact us to discuss how to do this. Brian Anderson Nick Holford -- Nick Holford, Dept Pharmacology & Clinical Pharmacology University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand email:n.holford http://www.health.auckland.ac.nz/pharmacology/staff/nholford/