Re: restart NONMEM
Bob,
The complexity of restarting NM7.2 when multiple $EST are used is really something that needs to be addressed within NONMEM.
Its not something I will be attempting with WFN.
Best wishes,
Nick
Quoted reply history
On 15/08/2012 11:46 p.m., Hiker Hiker wrote:
> Hi Nick,
> WFN provides a great support.
>
> NONMEM7.2 is complex. INTER file is empty sometimes. The restart commants may need some additional options when several methods are used in the same *.CTL file.
>
> Cheers,
> Bob
>
> *From:* Nick Holford <[email protected]>
> *To:* nmusers <[email protected]>
> *Sent:* Tuesday, August 14, 2012 3:19 PM
> *Subject:* Re: [NMusers] restart NONMEM
>
> Bob,
>
> First of all you need to restart your spell checker -- this is the NONMEM user group :-)
>
> WFN can help restart if you include the MSFO option in the $EST record.
>
> The nmctl command with the 'i' option will copy the intermediate output parameter estimates (using the INTER file) from the last iteration into the NM-TRAN control stream. You can then restart the run.
>
> Nick
>
> On 14/08/2012 11:28 p.m., Hiker Hiker wrote:
> >
> > Dear NONMEN Users:
> > What are the most efficient ways to restart NONMEM if it is
> > interrupted? NONMEM allows only one MSFO statement when several
> > methods are used.
> > Can supporting software packages such as PsN, xpose, wings of
> > NONMEM, etc. help?
> > Cheers,
> > Bob
> >
>
> -- Nick Holford, Professor Clinical Pharmacology
>
> First World Conference on Pharmacometrics, 5-7 September 2012
> Seoul, Korea http://www.go-wcop.org
>
> Dept Pharmacology & Clinical Pharmacology, Bldg 505 Room 202D
> University of Auckland,85 Park Rd,Private Bag 92019,Auckland,New Zealand
> tel:+64(9)923-6730 fax:+64(9)373-7090 mobile:+64(21)46 23 53
> email: [email protected] <mailto:[email protected]>
> http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford
--
Nick Holford, Professor Clinical Pharmacology
First World Conference on Pharmacometrics, 5-7 September 2012
Seoul, Korea http://www.go-wcop.org
Dept Pharmacology & Clinical Pharmacology, Bldg 505 Room 202D
University of Auckland,85 Park Rd,Private Bag 92019,Auckland,New Zealand
tel:+64(9)923-6730 fax:+64(9)373-7090 mobile:+64(21)46 23 53
email: [email protected]
http://www.fmhs.auckland.ac.nz/sms/pharmacology/holford