RE: How sparse is too sparse?

From: Nick Holford Date: June 10, 2004 technical Source: cognigencorp.com
From: Nick Holford n.holford@auckland.ac.nz Subject: RE:[NMusers] How sparse is too sparse? Date: Thu, June 10, 2004 3:46 pm Robert, Its unlikely you will be able to estimate much more than CL/F (and thus AUC if you want) from this kind of data. This is especially so if you only have trough samples. I cannot imagine that you would be able to estimate a lag time. At best you might be able to get CL/F, V/F and Ka. Perhaps this Pharm company would be better off Farming. Nick -- Nick Holford, Dept Pharmacology & Clinical Pharmacology University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand email:n.holford@auckland.ac.nz tel:+64(9)373-7599x86730 fax:373-7556 http://www.health.auckland.ac.nz/pharmacology/staff/nholford/

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Jun 10, 2004 Robert L. James How sparse is too sparse?
Jun 10, 2004 Leonid Gibiansky RE: How sparse is too sparse?
Jun 10, 2004 Fengyan RE: How sparse is too sparse?
Jun 10, 2004 Nick Holford RE: How sparse is too sparse?
Jun 10, 2004 Kenneth Kowalski RE: How sparse is too sparse?
Jun 10, 2004 Serge Guzy RE: How sparse is too sparse?
Jun 10, 2004 Serge Guzy RE: How sparse is too sparse?
Jun 11, 2004 Kenneth Kowalski RE: How sparse is too sparse?
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