some issues about NONMEM

From: Nick Holford - n.holford@auckland.ac.nz Subject Re: [NMusers] some issues about NONMEM Date: 2/12/2004 1:12 PM Marc, This fix was provided to me directly by Stuart after I had reported a problem to nmconsult. If you need this fix then it will be obvious because NM-TRAN produces illegal Fortran code and your compiler will complain. The fix is needed when using very large models which require larger array dimensions than were originally anticipated in FSUBS. The patches to GENCOM allow these larger arrays to be emitted by NM-TRAN. In my case it was triggered by using the $SUBROUTINE LIBRARY option with ADVAN6 with 50 THETA, 56 ETA and 3 EPS parameters. Nick -- Nick Holford, Dept Pharmacology & Clinical Pharmacology University of Auckland, 85 Park Rd, Private Bag 92019, Auckland, New Zealand email:n.holford@auckland.ac.nz tel:+64(9)373-7599x86730 fax:373-7556 http://www.health.auckland.ac.nz/pharmacology/staff/nholford/ _______________________________________________________