Re: A question about TOL
A suggested value in the NONMEM users guide (NM7.2) for TOL is 9 if you use NSIG=3 and SIGL=9
I would not want to use TOL<3 under any circumstance.
Quoted reply history
On 26/07/2012 6:11 a.m., Wang, Xiaofeng wrote:
> Hi all,
>
> I wonder if there is an acceptable smallest TOL value for ADVAN6 and what is it? I searched user guide but did not find the answer. Could anyone share some information? Thank you.
>
> Xiaofeng
--
Nick Holford, Professor Clinical Pharmacology
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