Peter Bonate

97 messages, 1998–2024

Date Subject
Mar 10, 1998 Covariate Model Selection technical
Mar 11, 1998 Covariate Model Selection II technical
Oct 07, 1998 Post-hoc distributions technical
Nov 13, 1998 Bioequivalence question technical
Dec 11, 1998 2 compartment MM technical
Feb 02, 1999 more on PREDvsDV technical
Feb 02, 1999 RE: more on PREDvsDV technical
Feb 02, 1999 RE: DV vs PRED: a question technical
Feb 02, 1999 yet another reply to pred vs. DV technical
Mar 25, 1999 comparing theta's technical
Apr 02, 1999 flip-flop kinetics technical
Mar 23, 2001 Rounding errors / $SIM superproblem technical
Apr 04, 2001 Lag Time Problem technical
May 31, 2001 Covariate screening technical
May 31, 2001 Covariate screening #2 technical
Jun 26, 2001 BQLs technical
Jul 05, 2001 Centering technical
Jul 27, 2001 One vs two compartments technical
Aug 16, 2001 S-matrix and RNGs technical
Jan 17, 2002 NONMEM testing set technical
Jun 28, 2002 Metabolite kinetics help technical
Jul 12, 2002 Wrong model technical
Jul 31, 2002 NMV on Pentium 4 technical
Oct 04, 2002 OMEGA HAS A NONZERO BLOCK technical
Oct 08, 2002 signficant covariate question technical
Oct 30, 2002 weight as a covariate in kids technical
Jun 11, 2003 When is PK not needed technical
Sep 25, 2003 order of covariate inclusion technical
Sep 25, 2003 Re: order of covariate inclusion technical
Sep 25, 2003 RE: Re: order of covariate inclusion technical
Oct 22, 2003 grid computing technical
Oct 23, 2003 Re: LLR test, AIC, BIC technical
Dec 17, 2003 Scaling of pharmacokinetics in peds technical
Jan 13, 2004 Fixed elements within a block covariance matrix technical
Jan 13, 2004 Fixed elements within a block covariance matrix technical
Feb 09, 2004 Time of day as a covariate technical
Feb 10, 2004 Re: Time of day as a covariate technical
Feb 13, 2004 Modeling average data technical
May 20, 2004 NONMEM Estimation algorithms technical
Aug 23, 2004 Decrease in OFV with a fixed effect technical
Oct 28, 2004 Most important papers in PopPK technical
Dec 08, 2004 RE: SAS program or SAS macro to prepare NonMem ready data technical
Dec 08, 2004 SAS vs S-Plus technical
May 19, 2005 Neutrophil transit models technical
Jun 20, 2005 Compaq Digital Fortran no more technical
Jul 05, 2005 RE: statistical basis of NONMEM technical
Sep 15, 2005 Interpreting IOV technical
Sep 30, 2005 MM elimination vs dose technical
Feb 01, 2006 100% CPU with NONMEM technical
Feb 28, 2006 Help on a cell transit model technical
May 02, 2006 leverage analysis vs. case deletion technical
May 25, 2006 Referenced memory could not be written error technical
Jul 18, 2006 Reporting of interim models in Pop PK Reports technical
Jul 31, 2006 Re: Problems with an apparent compiler-senstive model technical
Jul 31, 2006 Re: Problems with an apparent compiler-senstive model technical
Feb 07, 2007 Pred Exit Error =1 with $SIM technical
Mar 20, 2007 General question on modeling technical
Mar 29, 2007 input conversion error technical
May 10, 2007 Windows Vista technical
May 11, 2007 RE: Windows Vista technical
Jul 10, 2007 mid-infusion higher than end of infusion technical
Aug 29, 2007 sample size issue technical
Jan 02, 2008 RE: RE: re: bug in NONMEM VI? technical
Jan 07, 2008 RE: Antwort: PK/PD models to describe anti-ancer drug effect on the tumor volume technical
Jan 15, 2008 RE: "Connect the dots" approach for a time-varying covariate technical
Jul 01, 2008 Outstanding Paper in Modeling and Simulation technical
Jan 12, 2009 CrcL or Cr in pediatric model technical
Apr 02, 2009 Outstanding Manuscript in M&S technical
Apr 10, 2009 Quinidine dataset technical
Apr 23, 2009 Pharmacoeconomic simulations technical
Jun 30, 2009 Format for submission to FDA technical
Jun 30, 2009 Format for submission to FDA technical
Aug 11, 2010 Baseline as a covariate technical
Jul 21, 2011 Open Position for PKMS Modeler at Astellas job
Oct 18, 2011 help on problem with baseline estimation technical
Jun 04, 2012 RE: Problem in Simulation technical
Sep 09, 2014 Contributors needed for Themed Issue of Journal of PKPD technical
Oct 29, 2014 RE: Minimization Terminated in Bootstrapping technical
Nov 06, 2014 Open Position at Astellas: Associate Director/Senior Manager in PKMS job
Jan 21, 2015 A new book on Model Communication technical
May 06, 2015 RE: tracer-tracee kinetics technical
Sep 05, 2015 Re: RE: Estimation of ke0 from raw data technical
Jun 27, 2017 Themed issue on Recent technical
Feb 03, 2019 Re: Why should we avoid using micro rate constants? technical
Feb 04, 2019 Summer Internship Available at Astellas job
Apr 04, 2019 Post-Doctoral Fellowship in Artificial Intelligence in Clinical Pharmacology at Astellas job
Apr 04, 2019 Post-Doctoral Fellowship in Artificial Intelligence in Clinical Pharmacology at Astellas job
Nov 18, 2019 RE: AMD vs Intel technical
Jan 27, 2021 Post-Doctoral Fellowship in Artificial Intelligence in Clinical Pharmacology at Astellas job
Apr 29, 2021 RE: Assessment of elimination half life of mAb technical
Jan 13, 2022 Pharmacometrics or QSP summer internship at Astellas US in 2021 job
Sep 13, 2022 RE: flip-flop without absorption information? technical
Nov 29, 2022 RE: Condition number technical
Nov 30, 2022 Re: Condition number technical
Dec 01, 2022 RE: Condition number technical
Dec 01, 2023 Pharmacometrics summer internship at Astellas US job
Dec 04, 2024 RE: Historical question technical