RE: Historical question
Personally I don’t think it was the use of FOCEI that led to NONMEM taking off,
it was that you could run it on personal computers, which were just starting to
be powerful enough to handle to computational load. This was back when
computers had numbers for names, like 386 and 486. I think this started with
NONMEM IV.
There was a history of NONMEM webpage that Icon maintained, but when I checked
today, it no longer looks like it is functional.
https://nonmem.iconplc.com/nonmem_history/NONMEM_history4.pdf
Pete Bonate
Peter Bonate, PhD
Suzerain, New Technologies
Early Development
Astellas
2375 Waterview Drive
Northbrook, IL 60062
[email protected]<mailto:[email protected]>
(224) 619-4901
Quoted reply history
From: [email protected] <[email protected]> On Behalf Of
Eleveld, DJ
Sent: Wednesday, December 4, 2024 5:39 AM
To: nmusers <[email protected]>
Subject: [NMusers] Historical question
Hi All, I am writing a paper on some C language code I have written that does
FOCE. I want to write a few sentences about the history of NONMEM but I’m not
100% sure it is correct. Can someone knowledgeable give me some feedback on
this?
Hi All,
I am writing a paper on some C language code I have written that does FOCE.
I want to write a few sentences about the history of NONMEM but I’m not 100%
sure it is correct.
Can someone knowledgeable give me some feedback on this?
“NONMEM software was developed at USCF in the late 1970s and became the
de-facto industry standard when the first-order-conditional estimation with
interaction (FOCE-I) method reaching wide use in the field. NONMEM was open
source until version 5 when the rights were obtained by Icon PLC and it became
encrypted-source. The investment of Icon PLC has resulted in considerable
NONMEM development with many bug-fixes and new features available in current
version 7.5.1. ”
Warm regards,
Douglas Eleveld
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