Post-hoc distributions

From: Peter Bonate Date: October 07, 1998 technical Source: cognigencorp.com
From: "Bonate, Peter, HMR/US" <Peter.Bonate@hmrag.com> Subject: Post-hoc distributions Date: Wed, 7 Oct 1998 16:03:01 -0500 Maybe someone can explain something to me. Assume that you specify in your structural model that a parameter is log-normal distributed. Then you use first order estimation to get your post-hoc estimates for that parameter. Shouldn't the distribution of the post-hocs be log-normal as well? I have noticed that sometimes they are dramatically different. Thanks. PETER L. BONATE, PhD. Population Pharmacokinetics Hoechst Marion Roussel POB 9627 (F4-M3112) Kansas City, MO 64134 phone: 816-966-3723 fax: 816-966-6999

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Oct 07, 1998 Peter Bonate Post-hoc distributions
Oct 08, 1998 Lewis B. Sheiner Re: Post-hoc distributions
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