| Feb 17, 1994 |
Unknown Dosing Histories
technical
|
| Mar 07, 2002 |
RE: Error message..
technical
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| Mar 13, 2002 |
RE: NONMEM vs NLMIXED
technical
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| Mar 22, 2002 |
RE: Approximate effect compartment
technical
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| Mar 22, 2002 |
RE: Approximate effect compartment
technical
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| Apr 29, 2002 |
RE: When to do transformation of data?
technical
|
| Aug 23, 2002 |
RE: Imputation of missing sex covariate
technical
|
| Aug 26, 2002 |
RE: Imputation of missing sex covariate
technical
|
| Oct 02, 2002 |
RE: OMEGA HAS A NONZERO BLOCK
technical
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| Oct 03, 2002 |
RE: OMEGA HAS A NONZERO BLOCK
technical
|
| Oct 04, 2002 |
RE: FW: OMEGA HAS A NONZERO BLOCK
technical
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| Oct 04, 2002 |
RE: FW: OMEGA HAS A NONZERO BLOCK
technical
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| Oct 04, 2002 |
RE: FW: OMEGA HAS A NONZERO BLOCK
technical
|
| Oct 07, 2002 |
RE: OMEGA HAS A NONZERO BLOCK
technical
|
| Oct 07, 2002 |
RE: OMEGA HAS A NONZERO BLOCK
technical
|
| Oct 07, 2002 |
RE: OMEGA HAS A NONZERO BLOCK
technical
|
| Oct 07, 2002 |
RE: OMEGA HAS A NONZERO BLOCK
technical
|
| Oct 07, 2002 |
RE: OMEGA HAS A NONZERO BLOCK
technical
|
| Feb 14, 2003 |
RE: simulated negative concentration
technical
|
| Mar 05, 2003 |
RE: large CV
technical
|
| Mar 10, 2003 |
RE: Covariate effect
technical
|
| Apr 01, 2003 |
RE: Describing variability
technical
|
| Apr 01, 2003 |
RE: Describing variability
technical
|
| Apr 01, 2003 |
RE: Describing variability
technical
|
| Apr 01, 2003 |
RE: Describing variability
technical
|
| Apr 02, 2003 |
RE: Describing variability
technical
|
| Apr 02, 2003 |
RE: Describing variability
technical
|
| Apr 02, 2003 |
RE: Describing variability
technical
|
| Apr 02, 2003 |
RE: Describing variability
technical
|
| Apr 04, 2003 |
RE: Log-transformation
technical
|
| Apr 09, 2003 |
RE: Log-transformation
technical
|
| Apr 09, 2003 |
RE: Log-transformation
technical
|
| May 09, 2003 |
RE: from Ken Kowalski re: model diagnostics
technical
|
| Jun 02, 2003 |
RE: Obj. function is infinite (error=136)
technical
|
| Jul 18, 2003 |
RE: Re: FO vs FOCE vs LAPLACIAN
technical
|
| Jul 22, 2003 |
RE: Re: FO vs FOCE vs LAPLACIAN
technical
|
| Aug 05, 2003 |
RE: Non-physiological parameters at lowest OBJ
technical
|
| Aug 06, 2003 |
RE: Non-physiological parameters at lowest OBJ
technical
|
| Aug 07, 2003 |
RE: TVKa>TVKe or Ka>Ke?
technical
|
| Aug 08, 2003 |
RE: TVKa>TVKe or Ka>Ke?
technical
|
| Aug 11, 2003 |
RE: Ka>Ke?
technical
|
| Aug 19, 2003 |
RE: increasing ETA estimates with adding full block
technical
|
| Sep 25, 2003 |
RE: order of covariate inclusion
technical
|
| Sep 25, 2003 |
RE: order of covariate inclusion
technical
|
| Sep 26, 2003 |
RE: order of covariate inclusion -> avoiding stepwise approaches
technical
|
| Sep 26, 2003 |
RE: order of covariate inclusion -> avoiding stepwise approaches -> abandoning exploratory analysis?
technical
|
| Sep 26, 2003 |
RE: order of covariate inclusion -> avoiding stepwise approaches -> abandoning exploratory analysis?
technical
|
| Sep 29, 2003 |
RE: order of covariate inclusion -> avoiding stepwise approaches -> abandoning exploratory analysis?
technical
|
| Sep 29, 2003 |
RE: order of covariate inclusion -> avoiding stepwise a pproaches -> abandoning exploratory analysis?
technical
|
| Oct 17, 2003 |
RE: Re: Initial estimates query
technical
|
| Oct 23, 2003 |
Re: LLR test, AIC, BIC
technical
|
| Nov 21, 2003 |
RE: interpretation of WRES of logarithmically transformed data
technical
|
| Jan 13, 2004 |
RE: Fixed elements within a block covariance matrix
technical
|
| Jan 27, 2004 |
RE: simulation
technical
|
| Jun 02, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Jun 02, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Jun 03, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Jun 08, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Jun 08, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Jun 09, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Jun 10, 2004 |
RE: How sparse is too sparse?
technical
|
| Jun 10, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Jun 11, 2004 |
RE: How sparse is too sparse?
technical
|
| Jun 29, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Jul 02, 2004 |
RE: $OMEGA blocks and log-likelihood profiling
technical
|
| Aug 11, 2004 |
RE: COEFFICIENT MATRIX IS ALGORITHMICALLY SINGULAR
technical
|
| Aug 23, 2004 |
RE: Decrease in OFV with a fixed effect
technical
|
| Sep 21, 2004 |
RE: BOV
technical
|
| Sep 21, 2004 |
RE: BOV
technical
|
| Sep 22, 2004 |
RE: BOV
technical
|
| Sep 22, 2004 |
RE: BOV
technical
|
| Sep 22, 2004 |
RE: BOV
technical
|
| Sep 23, 2004 |
RE: BOV
technical
|
| Sep 23, 2004 |
RE: BOV
technical
|
| Sep 23, 2004 |
RE: BOV
technical
|
| Sep 24, 2004 |
RE: BOV
technical
|
| Dec 07, 2004 |
RE: posthoc step
technical
|
| Dec 08, 2004 |
RE: posthoc step
technical
|
| Apr 04, 2005 |
RE: population size and confidence power
technical
|
| May 13, 2005 |
RE: Probabilistic model
technical
|
| Jun 15, 2005 |
RE: Simulation vs. actual data
technical
|
| Jul 05, 2005 |
RE: Simulation vs. actual data
technical
|
| Jul 14, 2005 |
RE: Simulation vs. actual data
technical
|
| Jul 15, 2005 |
RE: Simulation vs. actual data
technical
|
| Jul 16, 2005 |
RE: Simulation vs. actual data
technical
|
| Aug 10, 2005 |
RE: Simulating different populations
technical
|
| Oct 06, 2005 |
Re: non-linear PK
technical
|
| Jan 19, 2006 |
RE: covariate selection question
technical
|
| Jan 20, 2006 |
RE: covariate selection question
technical
|
| Sep 27, 2006 |
RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION
technical
|
| Sep 28, 2006 |
RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION
technical
|
| Sep 29, 2006 |
RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION
technical
|
| Oct 02, 2006 |
RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION
technical
|
| Oct 02, 2006 |
RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION
technical
|
| Oct 03, 2006 |
RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION
technical
|
| Oct 03, 2006 |
RE: WRES AND OUTLIER IDENTIFICATION/EXCLUSION
technical
|
| Feb 15, 2008 |
RE: IIV on %CV-Scale - Standard Error (SE)
technical
|
| Apr 22, 2008 |
RE: truncation & simulation
technical
|
| Apr 23, 2008 |
RE: truncation & simulation
technical
|
| May 23, 2008 |
RE: Visual predictive check!
technical
|
| Nov 13, 2008 |
RE: NONMEM message
technical
|
| Nov 14, 2008 |
RE: Very small P-Value for ETABAR
technical
|
| Nov 21, 2008 |
RE: Models that abort before convergence Addendum
technical
|
| Dec 09, 2008 |
RE: FO vs FOCE, sequential vs simultaneous
technical
|
| Apr 21, 2009 |
RE: OMEGA selection
technical
|
| May 12, 2009 |
WAM v1.01 now available on NONMEM repository
news
|
| Aug 25, 2009 |
RE: What does convergence/covariance show?
technical
|
| Aug 26, 2009 |
RE: What does convergence/covariance show?
technical
|
| Feb 05, 2010 |
RE: Dilemma with PPK parameters
technical
|
| Mar 22, 2010 |
Modeling Webinar Announcement
event
|
| Aug 11, 2010 |
RE: Baseline as a covariate
technical
|
| Aug 12, 2010 |
RE: Effect of placebo or drug to the baseline value
technical
|
| Nov 01, 2010 |
RE: Rational of using IOV
technical
|
| Dec 19, 2010 |
RE: Negative OFV number
technical
|
| Jan 06, 2011 |
RE: outsourcing PK/PD analysis - help wanted
job
|
| Mar 01, 2011 |
RE: [Fwd: occasions during pregnancy]
technical
|
| Sep 21, 2011 |
RE: analysis of non-positive DV
technical
|
| Feb 06, 2012 |
RE: medians of the simulation in VPC are systematically below the medians of the observations when the model fit looks fine.
technical
|
| May 24, 2012 |
RE: Successful minimization and covariance
technical
|
| Jun 12, 2012 |
RE: omega matrix - friendly suggestion
technical
|
| Nov 08, 2012 |
RE: RE: Proper way to handle the pre-first dose PK observation for non-endogenous drug
technical
|
| Feb 20, 2013 |
RE: RE: Simulation settgin in the precence of Shrinkage in PK when doing PK-PD analysis
technical
|
| Feb 21, 2013 |
RE: RE: Simulation settgin in the precence of Shrinkage in PK when doing PK-PD analysis
technical
|
| Mar 29, 2014 |
RE: NONMEM vs SPSS
technical
|
| Sep 04, 2014 |
RE: Inflated random effects showed by VPC
technical
|
| Sep 25, 2014 |
RE: OMEGA matrix
technical
|
| Sep 30, 2014 |
RE: OMEGA matrix
technical
|
| Oct 01, 2014 |
RE: OMEGA matrix
technical
|
| Oct 02, 2014 |
RE: OMEGA matrix
technical
|
| Jun 08, 2015 |
RE: Fwd: Should we generate VPCs with or without uncertainty?
technical
|
| Nov 06, 2015 |
Re: eigenvalues
technical
|
| May 23, 2017 |
GoFundMe Site for the Hutmacher Family
technical
|
| May 25, 2017 |
Help for the Hutmacher Family
technical
|
| May 25, 2017 |
GoFundMe Site for the Hutmacher Family
technical
|
| Mar 14, 2019 |
RE: VPCs confidence intervals?
technical
|
| Jun 10, 2019 |
ACoP10 Post-Meeting Workshop: Integration of PHM and Stat Analyses Using CTS, October 24, 2019
event
|
| Jun 02, 2020 |
RE: Negative concentration from simulation
technical
|
| Mar 22, 2021 |
RE: Statistical power computation based on the wald test
technical
|
| Mar 24, 2021 |
RE: Statistical power of covariate inclusion in popPK models
technical
|
| Mar 24, 2021 |
RE: [EXTERNAL] RE: Statistical power computation based on the wald test
technical
|
| Nov 29, 2022 |
RE: Condition number
technical
|
| Nov 30, 2022 |
RE: Condition number
technical
|
| Dec 01, 2022 |
RE: Condition number
technical
|