RE: Error message..
From:"Kowalski, Ken"
Subject:RE: [NMusers] Error message..
Date:Thu, March 7, 2002 8:22 am
Emily,
The R matrix singular condition is an indication that your
model is over-parameterized, i.e., an infinite set of parameter values
in Theta, Omega and Sigma can result in the same value of the Objective Function.
I suggest that you re-check the coding of your model to verify that it is
correct and what you intended. If that is fine, you may have to reduce your model.
If you can provide the control stream as Sam suggests I'm sure
one or more NMUSERs will be happy to provide you
some suggestions on modifying your model.
Regarding the T matrix I could not find any description of it in
the NONMEM user's guides. Does anyone out there know?
I believe it is only reported when the R matrix singular condition
arises and presumably is a diagnostic that can help determine
the nature of the singularity.
Ken