RE: Ka>Ke?

From: Ken Kowalski <Ken.Kowalski@pfizer.com> Subject: RE: [NMusers] Ka>Ke? Date: 8/11/2003 8:52 AM Rik, I would agree with you that in terms of individual fits it doesn't really matter as you can always switch the parameters to get the identical fit. But I don't think that's true at the population level. For the FOCE method the estimates of the etas are also flipped and that's got to impact the approximation/estimation. Another way to look at it is suppose that you were doing a standard two-stage approach and a couple of your individual fits had flip-flop parameter estimates. You would want to reverse them before you averaged across the individuals to obtain the population estimates. Ken