RE: Simultaneous drug and metabolite POPPK
I have a question for those who submitted these two examples - Did you
transform the data into micromolar quantities? It is not clear from the
examples. I have not done much parent/metabolite modeling (just lucky I
guess) but it seems to me that one would have to work in molar units for
these models to be valid. Can someone comment on this?
Mike
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Michael J. Fossler, Pharm. D., Ph. D., F.C.P.
Director
Clinical Pharmacokinetics, Modeling & Simulation
GlaxoSmithKline
(610) 270 - 4797
FAX: (610) 270-5962
Cell: (443) 350-1194
[EMAIL PROTECTED]
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