Re: Indirect response PD model

From: "Sam Liao" sliao@pharmaxresearch.com Subject: Re: [NMusers] Indirect response PD model Date: Tue, February 1, 2005 2:45 pm Hi Max: If you used the plasma conc (Cp) in the data set to run this model, you need to do some sort of interpolation of the Cp within the $DES block. Otherwise, the solution of the PD effect compartment will not be correct because the ODE solver will use a step function instead of a continuous curve of Cp. Best regards, Sam Liao Pharmax Research _______________________________________________________