Re: posthoc step

From: "Nitin Kaila" kail0004@umn.edu Subject: Re: [NMusers] posthoc step Date: Mon, December 6, 2004 9:05 pm Hi Pravin: I am not sure if I understand your question correctly. In the simplest analytical approximation i.e. the first order (FO) method in NONMEM, all the etas are set to zero. Now what the POSTHOC option does is that it use the estimated population parameters as priors for an individual's data and computes the empirical bayesian post hoc estimates. This happens at the end of a normal FO run with the POSTHOC option. I hope this helps. Regards, Nitin Nitin Kaila Doctoral Candidate 308 Harvard St. SE 7-192 WDH Minneapolis, MN 55455 Department of Experimental and Clinical Pharmacology University of Minnesota PH: 612-624-9683 (office)