sample size
From: "Vijay V. Upreti"
Subject: [NMusers] sample size
Date: Thu, November 11, 2004 6:15 pm
Hi all,
I have this very simpe question regarding the minimum sample size for
population analysis.
I have plasma concentration time data from 4 large mammals. There are 10
sampling points and I was just wondering if I can use population analysis
for this small sample size.
I am aware that NONMEM can be used for modeling single subject data but will
n=4 suffice for population analysis, some thoughts please.
_______________
Vijay V Upreti
Gradaute Student
Pharmacokinetics-Biopharmaceutics Laboratory
Department of Pharmaceutical Sciences
University of Maryland, School of Pharmacy
20 Penn St., Baltimore, MD 21201
Voice: 410-706-7388
Fax: 410-706-5017