RE: sample size

From: Pascal Girard Date: November 14, 2004 technical Source: cognigencorp.com
From: "GIRARD PASCAL" PASCAL.GIRARD@adm.univ-lyon1.fr Subject: RE: [NMusers] sample size Date: Sun, November 14, 2004 4:31 am Hi Mats, I was certainly not recommanding STS neither. Having said this, does better means good estimates? I don't know the work you mention, but did you have a look at the confidence intervals? Did you know the exact structural and PK-PD model (simulated or real data set) ? How large were the random inter-individual variances? Did you have outliers? All this may affect your results with few individuals. That's why I was cautionning any population analysis (one or 2 stages) with only 4 individuals, unless you have adressed all those questions and accept to report your CI. Have a good Sunday, Pascal

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Nov 11, 2004 Vijay V. Upreti sample size
Nov 12, 2004 Serge Guzy RE: sample size
Nov 14, 2004 Pascal Girard RE: sample size
Nov 14, 2004 Mats Karlsson RE: sample size
Nov 14, 2004 Pascal Girard RE: sample size
Nov 14, 2004 Mats Karlsson RE: sample size
Nov 14, 2004 Stephen Duffull RE: sample size
Nov 15, 2004 Mats Karlsson RE: sample size
Nov 15, 2004 Stephen Duffull RE: sample size
Nov 15, 2004 Pascal Girard RE: sample size
Nov 15, 2004 Mats Karlsson RE: sample size
Nov 15, 2004 Stephen Duffull RE: sample size
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