Re[2]: covariate models
From Rene_Braeckman@cc.chiron.com Thu Jun 12 09:00:44 1997
Subject: Re[2]: covariate models
Height, weight, body surface area, gender, etc are all demographic covariates that might be tested whether they influence a particular PK parameter. Some of these covariates, if not all, can be interrelated, i.e., are not independent from each other or are correlated among each other. If weight and gender are both statistically significant covariates on V, you can indeed calculate typical values of V for a standard 70-kg male and a standard 70-kg female.
Rene Braeckman
Dept. of PK/PD, Chiron Corporation