NONMEM installation error on OS X EI Capitan

Dear NMusers, Recently I upgraded my Mac to OS X EI Capitan, yet this broke the installation of NONMEM like last year when I upgraded my Mac to Yosemite. I tried to reinstall NONMEM but with error. The following is how I did. 1) I prefer to take gcc/gfortran binaries from *High Performance Computing for Mac OS X *( http://hpc.sourceforge.net/)*. *The latest gcc/gfortran 5.2 for EI Capitan were installed by command *sudo tar -xvf gcc-5.2-bin.tar.gz -C /* and *sudo tar **-xvf gfortran-5.2-bin.tar.gz -C /*. This step was successful. I tested in terminal by running *gfortran -v*, it showed the right returns. 2) Then I tried to install NONMEM by command *sudo /bin/bash setup73 [NONMEM source path] [Target path] gfortran y /opt/local/bin/ar same rec i unzip nonmem73e.zip nonmem73r.zip*. When it came to *Step 10. Build NONMEM archive nm/nonmem.a*, it showed like this: *Step 10. Build NONMEM archive nm/nonmem.a* *NMTRAN.exe was not created Please look for error messages in /opt/nm73/compilemsgs.txt and /opt/nm73/finishmsgs.txtInstallation Aborted* The attachments are *compilemsgs.txt* and *finishmsgs.txt*. I'm not very clear about the error messages, it seems that there is still something wrong with gcc/gfortran. There is nothing different in setting gcc/gfortran this time compare to before. So I have no idea about this issue. Is there any experience about this problem? And any advice would be appreciated. Thanks! Tingjie *Tingjie Guo* M.S. Candidate Peking University/Pfizer Pharmacometrics Education Centre Department of Pharmaceutics, School of Pharmaceutical Sciences Peking University, Beijing, China /var/tmp//cctEGrMf.s:118:suffix or operands invalid for `movq' /var/tmp//cctEGrMf.s:119:suffix or operands invalid for `movq' ar: creating archive nonmem.a /opt/local/bin/ranlib: file: nonmem.a(BTOOLS4part031.o) has no symbols nonmem.a has been created /var/tmp//ccR9zoZV.s:311:suffix or operands invalid for `movq' /var/tmp//ccR9zoZV.s:431:suffix or operands invalid for `movq' /var/tmp//ccR9zoZV.s:5348:suffix or operands invalid for `movq' /var/tmp//ccR9zoZV.s:5364:suffix or operands invalid for `movq' Undefined symbols for architecture x86_64: "_getif_", referenced from: _getstm_ in GETSTM.o "_libinf_", referenced from: _genlib_ in GENLIB.o "_omsig_", referenced from: _MAIN__ in NMTRAN.o "_omsig_reorder_", referenced from: _genera_ in GENERA.o ld: symbol(s) not found for architecture x86_64 collect2: error: ld returned 1 exit status NMTRAN.exe has been created /var/tmp//cc5fWwpp.s:1881:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:1884:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:1894:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:1897:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:1907:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:1910:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:1920:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:1923:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:2859:suffix or operands invalid for `movq' /var/tmp//cc5fWwpp.s:2861:suffix or operands invalid for `movq' gfortran: error: finedata.o: No such file or directory cp: SIG and sig are identical (not copied). cp: TABLE_TO_XML and table_to_xml are identical (not copied). cp: TABLE_COMPARE and table_compare are identical (not copied). cp: XML_COMPARE and xml_compare are identical (not copied). cp: finedata: No such file or directory cp: NMTEMPLATE and nmtemplate are identical (not copied). /var/tmp//ccCMP09L.s:273:suffix or operands invalid for `movq' /var/tmp//ccCMP09L.s:375:suffix or operands invalid for `movq' /var/tmp//ccCMP09L.s:1512:suffix or operands invalid for `movq' /var/tmp//cclcqUnn.s:546:suffix or operands invalid for `movq' /var/tmp//cclcqUnn.s:547:suffix or operands invalid for `movq' /var/tmp//cclcqUnn.s:569:suffix or operands invalid for `movq' /var/tmp//cc0drNHe.s:2838:suffix or operands invalid for `movq' /var/tmp//ccvZAj06.s:158:suffix or operands invalid for `movq' /var/tmp//ccvZAj06.s:176:suffix or operands invalid for `movq' /var/tmp//ccnXschJ.s:628:suffix or operands invalid for `movq' /var/tmp//ccnXschJ.s:631:suffix or operands invalid for `movq' /var/tmp//ccZfvk1w.s:228:suffix or operands invalid for `movq' /var/tmp//ccZfvk1w.s:304:suffix or operands invalid for `movq' /var/tmp//ccZfvk1w.s:1012:suffix or operands invalid for `movq' /var/tmp//ccZfvk1w.s:1015:suffix or operands invalid for `movq' /var/tmp//cc4pWllV.s:516:suffix or operands invalid for `movq' /var/tmp//cc4pWllV.s:520:suffix or operands invalid for `movq' /var/tmp//cc4pWllV.s:3805:suffix or operands invalid for `movq' /var/tmp//cc4pWllV.s:3808:suffix or operands invalid for `movq' /var/tmp//cc4pWllV.s:3845:suffix or operands invalid for `movq' /var/tmp//ccvN0BI5.s:3437:suffix or operands invalid for `movq' /var/tmp//ccvN0BI5.s:3468:suffix or operands invalid for `movq' /var/tmp//ccaysfHQ.s:4659:suffix or operands invalid for `movq' /var/tmp//ccaysfHQ.s:4929:suffix or operands invalid for `movq' /var/tmp//ccD5p3vZ.s:6334:suffix or operands invalid for `movq' /var/tmp//ccD5p3vZ.s:6352:suffix or operands invalid for `movq' /var/tmp//ccD5p3vZ.s:6664:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:554:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:564:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:575:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:583:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:887:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:900:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:913:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:940:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:951:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:964:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:1586:suffix or operands invalid for `movq' /var/tmp//cc8DcJHy.s:1725:suffix or operands invalid for `movq' /var/tmp//ccMjk1Pe.s:2906:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2234:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2239:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2286:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2288:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2384:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2490:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2508:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2530:suffix or operands invalid for `movq' /var/tmp//cc3jm360.s:2532:suffix or operands invalid for `movq' /var/tmp//ccoYHsig.s:347:suffix or operands invalid for `movq' /var/tmp//ccoYHsig.s:366:suffix or operands invalid for `movq' /var/tmp//cc2qmMJX.s:166:suffix or operands invalid for `movq' /var/tmp//cc2qmMJX.s:207:suffix or operands invalid for `movq' /var/tmp//cc2qmMJX.s:240:suffix or operands invalid for `movq' /var/tmp//cc2qmMJX.s:273:suffix or operands invalid for `movq' /var/tmp//cc2qmMJX.s:1173:suffix or operands invalid for `movq' /var/tmp//cc2qmMJX.s:1791:suffix or operands invalid for `movq' /var/tmp//cc2qmMJX.s:7075:suffix or operands invalid for `movq' /var/tmp//cc2qmMJX.s:7088:suffix or operands invalid for `movq' /var/tmp//cccyQPGa.s:1441:suffix or operands invalid for `movq' /var/tmp//cccyQPGa.s:1465:suffix or operands invalid for `movq' /var/tmp//ccG5EbJx.s:4857:suffix or operands invalid for `movq' /var/tmp//ccG5EbJx.s:4871:suffix or operands invalid for `movq' /var/tmp//ccG5EbJx.s:4908:suffix or operands invalid for `movq' /var/tmp//ccG5EbJx.s:5966:suffix or operands invalid for `movq' /var/tmp//ccE2rJOn.s:1201:suffix or operands invalid for `movq' /var/tmp//ccLZEcOy.s:357:suffix or operands invalid for `movq' /var/tmp//ccfJFLPF.s:230:suffix or operands invalid for `movq' /var/tmp//ccfJFLPF.s:261:suffix or operands invalid for `movq' /var/tmp//cc8TCky5.s:2364:suffix or operands invalid for `movq' /var/tmp//cc8TCky5.s:2368:suffix or operands invalid for `movq' /var/tmp//cc8TCky5.s:2406:suffix or operands invalid for `movq' /var/tmp//cc8TCky5.s:2840:suffix or operands invalid for `movq' /var/tmp//ccjMX6iM.s:265:suffix or operands invalid for `movq' /var/tmp//ccjMX6iM.s:533:suffix or operands invalid for `movq' /var/tmp//ccDhovyT.s:164:suffix or operands invalid for `movq' /var/tmp//ccDhovyT.s:219:suffix or operands invalid for `movq' /var/tmp//ccwqbcVk.s:1231:suffix or operands invalid for `movq' /var/tmp//ccl4j3aP.s:1147:suffix or operands invalid for `movq' /var/tmp//ccl4j3aP.s:1179:suffix or operands invalid for `movq' /var/tmp//ccl4j3aP.s:1635:suffix or operands invalid for `movq' /var/tmp//ccssTgHr.s:3741:suffix or operands invalid for `movq' /var/tmp//ccssTgHr.s:3763:suffix or operands invalid for `movq' /var/tmp//ccssTgHr.s:6883:suffix or operands invalid for `movq' /var/tmp//ccssTgHr.s:6900:suffix or operands invalid for `movq' /var/tmp//ccDahuya.s:62:suffix or operands invalid for `movq' /var/tmp//ccDahuya.s:88:suffix or operands invalid for `movq' /var/tmp//ccXPURja.s:26:suffix or operands invalid for `movq' /var/tmp//ccXPURja.s:48:suffix or operands invalid for `movq' /var/tmp//ccXPURja.s:150:suffix or operands invalid for `movq' /var/tmp//ccXPURja.s:219:suffix or operands invalid for `movq' /var/tmp//ccXPURja.s:233:suffix or operands invalid for `movq' /var/tmp//ccXPURja.s:352:suffix or operands invalid for `movq' /var/tmp//ccXPURja.s:363:suffix or operands invalid for `movq' /var/tmp//ccXPURja.s:424:suffix or operands invalid for `movq' /var/tmp//ccwZsSkt.s:424:suffix or operands invalid for `movq' /var/tmp//ccwZsSkt.s:441:suffix or operands invalid for `movq' /var/tmp//ccHGnFSY.s:520:suffix or operands invalid for `movq' /var/tmp//ccHGnFSY.s:521:suffix or operands invalid for `movq' /var/tmp//ccHGnFSY.s:899:suffix or operands invalid for `movq' /var/tmp//ccHGnFSY.s:907:suffix or operands invalid for `movq' /var/tmp//ccHGnFSY.s:1034:suffix or operands invalid for `movq' /var/tmp//ccHGnFSY.s:1113:suffix or operands invalid for `movq' /var/tmp//ccHGnFSY.s:1179:suffix or operands invalid for `movq' /var/tmp//ccHGnFSY.s:1208:suffix or operands invalid for `movq' /var/tmp//ccA33hLJ.s:5788:suffix or operands invalid for `movq' /var/tmp//ccA33hLJ.s:5802:suffix or operands invalid for `movq' /var/tmp//ccA33hLJ.s:6621:suffix or operands invalid for `movq' /var/tmp//ccA33hLJ.s:6627:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:204:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:208:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:727:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:729:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:810:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:840:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:901:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:930:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1001:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1004:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1130:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1138:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1150:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1157:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1162:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1164:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1173:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1174:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1202:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1207:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1208:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1213:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1253:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1258:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1259:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1265:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1285:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1404:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1407:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1488:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1492:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1499:suffix or operands invalid for `movq' /var/tmp//ccvOok9w.s:1502:suffix or operands invalid for `movq' /var/tmp//ccR2TqF1.s:1462:suffix or operands invalid for `movq' /var/tmp//ccR2TqF1.s:1481:suffix or operands invalid for `movq' /var/tmp//ccLDy03m.s:89:suffix or operands invalid for `movq' /var/tmp//ccLDy03m.s:114:suffix or operands invalid for `movq' /var/tmp//cczSyBkC.s:1741:suffix or operands invalid for `movq' /var/tmp//cczSyBkC.s:1835:suffix or operands invalid for `movq' /var/tmp//cczSyBkC.s:2296:suffix or operands invalid for `movq' /var/tmp//cczSyBkC.s:2338:suffix or operands invalid for `movq' /var/tmp//ccnwnQNR.s:82:suffix or operands invalid for `movq' /var/tmp//ccTowERq.s:37:suffix or operands invalid for `movq' /var/tmp//ccTowERq.s:88:suffix or operands invalid for `movq' /var/tmp//ccwqIxUr.s:342:suffix or operands invalid for `movq' /var/tmp//ccwqIxUr.s:356:suffix or operands invalid for `movq' /var/tmp//ccwqIxUr.s:364:suffix or operands invalid for `movq' /var/tmp//ccwqIxUr.s:396:suffix or operands invalid for `movq' /var/tmp//ccwqIxUr.s:410:suffix or operands invalid for `movq' /var/tmp//ccwqIxUr.s:418:suffix or operands invalid for `movq' /var/tmp//ccjIKRTo.s:2676:suffix or operands invalid for `movq' /var/tmp//ccjIKRTo.s:2707:suffix or operands invalid for `movq' /var/tmp//ccjIKRTo.s:14734:suffix or operands invalid for `movq' /var/tmp//ccjIKRTo.s:18037:suffix or operands invalid for `movq' /var/tmp//ccjIKRTo.s:20313:suffix or operands invalid for `movq' /var/tmp//ccjIKRTo.s:20811:suffix or operands invalid for `movq' /var/tmp//ccjIKRTo.s:20881:suffix or operands invalid for `movq' /var/tmp//ccjIKRTo.s:21248:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:193:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:197:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:712:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:746:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:751:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:768:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:771:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:778:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:779:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:782:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:787:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:800:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:921:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:943:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1047:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1134:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1137:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1387:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1395:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1405:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1409:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1424:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1429:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1434:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1475:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1485:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1489:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1542:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1555:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1558:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1563:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1610:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1637:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1727:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1730:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1739:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1742:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1749:suffix or operands invalid for `movq' /var/tmp//ccz3greN.s:1753:suffix or operands invalid for `movq' install program 1.0 is finished

Alison Boeckmann will attempt to install El Capitan on her Mac to determine what needs to be done. Meanwhile, did you also update to the corresponding version of Xcode? Robert J. Bauer, Ph.D. Vice President, Pharmacometrics R&D ICON Early Phase Office: (215) 616-6428 Mobile: (925) 286-0769 [email protected]<mailto:[email protected]> http://www.iconplc.com