Correcting for salt vs. base

Colleagues I have been troubled by a minor issue for some time. Consider the following situation: Dose is reported in mg salt Cp is reported in ng/ml base Since CL is dose / AUC and AUC is merely the integral of Cp vs. time, in theory, dose should be converted to mg base (or concentration to ng/ml salt). However, I am not sure if everyone does that. In fact, an argument against it is that not doing the conversion permits one to relate the administered dose (which is usually based on salt) to a Cp value (usually based on base). I am interested to hear what approach people use. Dennis Dennis Fisher MD P < (The "P Less Than" Company) Phone: 1-866-PLessThan (1-866-753-7784) Fax: 1-866-PLessThan (1-866-753-7784) www.PLessThan.com