RE: Error in NONMEM 7.2 run
Rebecca:
As there is no precise information about the error, it is possible that NONMEM
flagged it because a predictive value of F returned an Infinity or Not a
number. This could have been cause by a divide by 0 somewhere, or log of a
negative number, etc. You should check your code.
Robert J. Bauer, Ph.D.
Vice President, Pharmacometrics, R&D
ICON Development Solutions
7740 Milestone Parkway
Suite 150
Hanover, MD 21076
Tel: (215) 616-6428
Mob: (925) 286-0769
Email: [email protected]
Web: http://www.iconplc.com/
Quoted reply history
________________________________
From: [email protected] [mailto:[email protected]] On
Behalf Of Rebecca.L.Neal
Sent: Tuesday, July 31, 2012 2:31 PM
To: [email protected]
Subject: [NMusers] Error in NONMEM 7.2 run
All,
I am developing a PKPD model and am getting the below error message. Any
suggestions or guidance would be appreciated. Thanks!
Rebecca Burns
Mercer University
Post-Doc
0PRED EXIT CODE = 1: Problem=1 Subproblem=0 Superproblem1=0 Iteration1=0
Superproblem2=0 Iteration2=0
0INDIVIDUAL NO. 1 ID= 1.00000000000000E+00 (WITHIN-INDIVIDUAL) DATA
REC NO. 1
THETA=
2.56E+00 7.53E+00 4.70E+01 -4.70E+01 2.34E+00 4.06E+01 1.00E+02
1.03E+03 5.98E+01 9.29E+03
2.57E+01 -8.08E+01 4.54E+01 6.33E+03 5.02E+01 9.06E+03 1.14E+02
7.60E+04 4.22E+01 1.19E+04
OCCURS DURING SEARCH FOR ETA AT INITIAL VALUE, ETA=0
0END OF PRED EXIT CODE MESSAGES FROM THE ESTIMATION STEP
0END OF MESSAGES: Problem=2 Subproblem=0 Superproblem1=0 Iteration1=0
Superproblem2=0 Iteration2=0
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