Very small P-Value for ETABAR

From: Jian Xu Date: November 13, 2008 technical Source: mail-archive.com
Dear NMUSERS, A few years back, there was a discussion on the P-value for ETABAR. However, I am not sure how to appropriately handle very small P-value(s) for ETABAR situation during the development of a model. I need some clarifications to a few questions: 1: Should we just ignore this small P-Value warning? 2: Can we change IIV model to avoid small P-value for ETABAR? Or any other suggestions? 3: Does NONMEM make any assumptions on ETA distribution? This P-value for ETABAR really bugs me a lot. I look forward to seeing some input. Thank you and I appreicate your time and help. Jian
Nov 13, 2008 Jian Xu Very small P-Value for ETABAR
Nov 13, 2008 Bill Denney RE: Very small P-Value for ETABAR
Nov 13, 2008 Pankaj Gupta RE: Very small P-Value for ETABAR
Nov 13, 2008 Jakob Ribbing RE: Very small P-Value for ETABAR
Nov 13, 2008 Yaning Wang RE: Very small P-Value for ETABAR
Nov 13, 2008 Leonid Gibiansky Re: Very small P-Value for ETABAR
Nov 13, 2008 Nick Holford Re: Very small P-Value for ETABAR
Nov 13, 2008 Xia LI Re: Very small P-Value for ETABAR
Nov 13, 2008 Kyun-seop Bae RE: Very small P-Value for ETABAR
Nov 14, 2008 Nick Holford Re: Very small P-Value for ETABAR
Nov 14, 2008 Jakob Ribbing RE: Very small P-Value for ETABAR
Nov 14, 2008 Mats Karlsson RE: Very small P-Value for ETABAR
Nov 14, 2008 Kenneth Kowalski RE: Very small P-Value for ETABAR
Nov 14, 2008 Xia Li RE: Very small P-Value for ETABAR
Nov 14, 2008 Leonid Gibiansky Re: Very small P-Value for ETABAR
Nov 17, 2008 Xia LI Re: Very small P-Value for ETABAR
Nov 17, 2008 Nick Holford Re: Very small P-Value for ETABAR
Nov 17, 2008 Jakob Ribbing RE: Very small P-Value for ETABAR
Nov 17, 2008 Matt Hutmacher RE: Very small P-Value for ETABAR
Nov 17, 2008 Xia Li RE: Very small P-Value for ETABAR
Nov 18, 2008 Xia Li RE: Very small P-Value for ETABAR