Re: dataset codification

Dear Mark, You may want to read about "EVID" in the html help. EVID = 4 is what you mean. It is a dosing event but implies that the system is reset before the dose is introduced into the system. Sebastien Mark Gutierrez a écrit : > Dear all, > > I am modeling some PK data from one rabbit. And I have some doubts how to codify the dataset. The rabbit received different single doses of a drug at different times. > > E.g, > > First of May it received a 100 mg dose i.v. , > > Then, 2 months latter (enough washout period), the first of July, it received and oral dose of 100mg.. > > Finally, after other two months the rabbit received the last oral dose 200mg. > > I could codify in the TIME column the real times, including the jumps of two months, but I think that there is an option in Nonmem to “restart” the dose through the dataset. Could somebody clarify me this point? and perhaps include a simple example of dataset. > > Thank you in advance > > Mark