dataset codification
Dear all,
I am modeling some PK data from one rabbit. And I have some doubts how to
codify the dataset. The rabbit received different single doses of a drug at
different times.
E.g,
First of May it received a 100 mg dose i.v. ,
Then, 2 months latter (enough washout period), the first of July, it received
and oral dose of 100mg.
Finally, after other two months the rabbit received the last oral dose 200mg.
I could codify in the TIME column the real times, including the jumps of two
months, but I think that there is an option in Nonmem to “restart” the dose
through the dataset.
Could somebody clarify me this point? and perhaps include a simple example of
dataset.
Thank you in advance
Mark