Re: Time of day as a covariate

From: michael.looby@pharma.novartis.com Subject: Re: [NMusers] Time of day as a covariate Date: 2/10/2004 2:24 AM Pete, Just to add to Nick's comments below, would this "statistically significant" difference merit a change in dose depending on the time of day the drug is administered? If not, does it need to or should it even enter the label? Mick