RE: Describing variability

From: VPIOTROV@PRDBE.jnj.com Subject: RE: [NMusers] Describing variability Date:Tue, 1 Apr 2003 13:36:05 +0200 Nick, Did I understand you correctly you accept FOCE results even if the run stops due to rounding errors, which is so common in NONMEM V (hopefully, it will be fixed somehow in NONMEM VI)? The same question to other nmusers: how do you cope with annoying rounding errors associated with FOCE, which are especially common in case of dense data? Best regards, Vladimir ----------------------------------------------------------------- Vladimir Piotrovsky, Ph.D. Research Fellow, Advanced PK-PD Modeling & Simulation Global Clinical Pharmacokinetics and Clinical Pharmacology Johnson & Johnson Pharmaceutical Research & Development Turnhoutseweg 30 B-2340 Beerse Belgium Tel: (+3214) 605463 Fax: (+3214) 605834 Email: vpiotrov@prdbe.jnj.com