RE: metabolite modeling

From: Sandra R B Allerheiligen Date: December 10, 1999 technical Source: cognigencorp.com
Date: Fri, 10 Dec 1999 12:34:05 -0500 From: Sandra R B Allerheiligen <ALLERHEILIGEN_SANDRA_R_B@Lilly.com> Subject: RE: metabolite modeling Hi Matt We have simulatanous analyzed a number of parent and metabolite profiles. I am not clear how you could get meaningful parameter estimates for the metabolite without simultaneously fitting the parent concentrations in addition to having some way on knowing the fraction of parent molecule clearance that reflects the formation rate. Regards Sandy A
Dec 09, 1999 Dick Wixley metabolite modelling
Dec 09, 1999 Stephen Duffull Re: metabolite modelling
Dec 09, 1999 Alison Boeckmann Re: metabolite modelling
Dec 09, 1999 Matt Hutmacher RE: metabolite modeling
Dec 09, 1999 David Bourne RE: metabolite modeling
Dec 09, 1999 Stephen Duffull Re: metabolite modeling
Dec 09, 1999 Matt Hutmacher RE: metabolite modeling
Dec 10, 1999 Mats Karlsson Re: metabolite modeling
Dec 10, 1999 Matt Hutmacher RE: metabolite modeling
Dec 10, 1999 Sandra R B Allerheiligen RE: metabolite modeling
Dec 13, 1999 Leon Aarons RE: metabolite modeling
Dec 13, 1999 Nick Holford Re: metabolite modeling
Dec 16, 1999 Stephen Duffull Re: metabolite modeling
Dec 17, 1999 Vladimir Piotrovskij RE: metabolite modeling
Dec 17, 1999 Jean Xavier Mazoit metabolite modeling
Dec 17, 1999 Nick Holford Re: metabolite modeling
Dec 17, 1999 Lewis B. Sheiner Re: metabolite modeling