NM-Tran infer data are single subject when perform simulation

On 10/29/2015 3:03 PM, Tommy Li wrote: > Hello > > I have population data set that I fitted to a model. However, when I try > to use the exact data set and model to perform simulation, I encounter > the situation where NM-Tran infer the data as single subject. Is there a > reason why this happens? Also, how do I force NM-Tran to infer data as > population for simulation in this case? > > To perform simulation I just change from $EST to $SIM. I have done this > before with other model and data set before with no problem. I did the > same with current model. > > Here is the beginning and end of my model code: > $INPUT ID PART TRT PTIM PTM2 TM TSLD AMT D FLAG CMT FBQL EVID MDV AGE > SEX WGT HGT BSA DIAB HTN HLIP ETOH SMOK BDAS BSJC BTJC BCRP WBC ALB ALT > AST CRCL ACR20 ACR50 ACR70 TIME TIME_ DV DV_ ACR50C ACR50P ACR70C ACR70P > KAI CLI VI > > $DATA pddataACRTIMECOR.csv IGNORE=@ > > $SUBROUTINES ADVAN6 TOL=10 > $SUBROUTINES OTHER=bivariate.f90 > > $MODEL NCOMP=3 COMP=DEPOT COMP=CENTRAL COMP=EFFECT > $PK > ..... > $ERROR > ..... > $THETA > ..... > $OMEGA > ..... > $EST MAX=8000 PRINT=2 METHOD=1 LAPLACE -2LL SIGL=10 NOHABORT > $COV COMPRESS MATRIX=R PRINT=E UNCONDITIONAL > > For simulation, I just change the $EST block to $SIM > $SIM (547676) (523842) ONLYSIM SUBPROBLEMS=1 > > Thank you > Tommy Li

From: [email protected] [mailto:[email protected]] On Behalf Of Tommy Li Sent: Thursday, October 29, 2015 15:04 To: “[email protected]” Subject: [NMusers] NM-Tran infer data are single subject when perform simulation Hello I have population data set that I fitted to a model. However, when I try to use the exact data set and model to perform simulation, I encounter the situation where NM-Tran infer the data as single subject. Is there a reason why this happens? Also, how do I force NM-Tran to infer data as population for simulation in this case? To perform simulation I just change from $EST to $SIM. I have done this before with other model and data set before with no problem. I did the same with current model. Here is the beginning and end of my model code: $INPUT ID PART TRT PTIM PTM2 TM TSLD AMT D FLAG CMT FBQL EVID MDV AGE SEX WGT HGT BSA DIAB HTN HLIP ETOH SMOK BDAS BSJC BTJC BCRP WBC ALB ALT AST CRCL ACR20 ACR50 ACR70 TIME TIME_ DV DV_ ACR50C ACR50P ACR70C ACR70P KAI CLI VI $DATA pddataACRTIMECOR.csv IGNORE=@ $SUBROUTINES ADVAN6 TOL=10 $SUBROUTINES OTHER=bivariate.f90 $MODEL NCOMP=3 COMP=DEPOT COMP=CENTRAL COMP=EFFECT $PK ..... $ERROR ..... $THETA ..... $OMEGA ..... $EST MAX=8000 PRINT=2 METHOD=1 LAPLACE -2LL SIGL=10 NOHABORT $COV COMPRESS MATRIX=R PRINT=E UNCONDITIONAL For simulation, I just change the $EST block to $SIM $SIM (547676) (523842) ONLYSIM SUBPROBLEMS=1 Thank you Tommy Li This electronic transmission may contain confidential and/or proprietary information and is intended to be for the use of the individual or entity named above. If you are not the intended recipient, be aware that any disclosure, copying, distribution or use of the contents of this electronic transmission is prohibited. If you have received this electronic transmission in error, please destroy it and immediately notify us of the error. Thank you.