NM-Tran infer data are single subject when perform simulation
Hello
I have population data set that I fitted to a model. However, when I try to
use the exact data set and model to perform simulation, I encounter the
situation where NM-Tran infer the data as single subject. Is there a reason
why this happens? Also, how do I force NM-Tran to infer data as population
for simulation in this case?
To perform simulation I just change from $EST to $SIM. I have done this
before with other model and data set before with no problem. I did the same
with current model.
Here is the beginning and end of my model code:
$INPUT ID PART TRT PTIM PTM2 TM TSLD AMT D FLAG CMT FBQL EVID MDV AGE SEX
WGT HGT BSA DIAB HTN HLIP ETOH SMOK BDAS BSJC BTJC BCRP WBC ALB ALT AST
CRCL ACR20 ACR50 ACR70 TIME TIME_ DV DV_ ACR50C ACR50P ACR70C ACR70P KAI
CLI VI
$DATA pddataACRTIMECOR.csv IGNORE=@
$SUBROUTINES ADVAN6 TOL=10
$SUBROUTINES OTHER=bivariate.f90
$MODEL NCOMP=3 COMP=DEPOT COMP=CENTRAL COMP=EFFECT
$PK
.....
$ERROR
.....
$THETA
.....
$OMEGA
.....
$EST MAX=8000 PRINT=2 METHOD=1 LAPLACE -2LL SIGL=10 NOHABORT
$COV COMPRESS MATRIX=R PRINT=E UNCONDITIONAL
For simulation, I just change the $EST block to $SIM
$SIM (547676) (523842) ONLYSIM SUBPROBLEMS=1
Thank you
Tommy Li