We are procuring a Zeos Pentium-based machine in our laboratory at the
University of Minnesota, and are intending to install NONMEM on it. Does anyone
have any advice/suggestions, either pro or con, regarding fortran compilers or
choice of operating systems? Any guidance would be appreciated.
FORTRAN compilers on Pentium machines
Really depends on computer RAM and other applications you want to run:
OS/2 2.1: Probabaly best if computer memory <=16Mb. Fortran apps can be
run using the free GNU f2c fortran pre-processor and gcc compilers
available using anonymous ftp to ftp-os2.nmsu.edu at New Mexico State
Univ. OS/2 runs DOS, Win 3.1 and (of course, if you can find them) OS/2
apps very well.
Windows NT 3.1 (1.0? :)) w/ service pack available at ftp.microsoft.com:
Probably best if computer memory >=16Mb (a real memory buster).
PowerStation Fortran from MS can make 32 bit apps, and some nmusers have
been giving tips via this forum for several months (thanks alison!). GNU
software as above is available on a CD from a company called Concurrent
(I think).
See
topic 2
for discussion of Powerstation compiler options
If you prefer a commercial Fortran compiler, I've had good luck with
Microway products. They also make compilers for other Intel operating
systems (DOS, Unix, etc). The only # I have is old, but should still
work: (508)746-7341.
Any one try to run NONMEM on a PowerMac yet? Bought one last week, and
it is one fast son-of-a-gun.
> OS/2 2.1: Probabaly best if computer memory <=16Mb. Fortran apps can be
> run using the free GNU f2c fortran pre-processor and gcc compilers
> available using anonymous ftp to ftp-os2.nmsu.edu at New Mexico State
> Univ. OS/2 runs DOS, Win 3.1 and (of course, if you can find them) OS/2
> apps very well.
Can you explain your strange remark that less RAM is better?
I would also caution about the use of f2c. I have used it to create a C
version of NONMEM that ran about half as fast as the original FORTRAN
code. That was on a Silicon Graphics irix4d MIPS etc processor.
If anyone has NONMEM running under OS/2 I have a benchmark problem that
has been tried on a range of machines thatI would like to try under
OS/2. Please contact me if you would be willing to help.
> Microway products. They also make compilers for other Intel operating
> systems (DOS, Unix, etc). The only # I have is old, but should still
> work: (508)746-7341.
>
The above number is correct. Also you can try email to mark@microway.com
or fax (508) 746 4678.
I would be really interested to know if anyone has any recent experience
with their NDP Fortran 486 or even i860 compilers with NONMEM.
I am using power station on Compaq pentium m/c and Have no problem. I
found getting extra cache increase the speed too. A pentium machine with
256 K cache was about 4 times faster than the 486/66 machine with a 68K
cache. I am running big data sets (400 patients about 10 conc per
patients and 20 inputs per patient) for 6-9 parameters it takes about 12
minutes under power station. Use Alison and Jaap's compilation
recommndation to get correct answer.
See
topic 2
for discussion of Powerstation compiler options