books/courses for learning popPK, PK/PD

From: [email protected] <[email protected]> On Behalf Of Magyar Gabriella dr. Sent: Friday, February 2, 2024 3:32 AM To: [email protected] Subject: [NMusers] books/courses for learning popPK, PK/PD Dear NMUsers, I would like to learn popPK (and PK/PD in the long-term) to a level to be able to build models on my own. Now I'm on the level that I mostly understand the models built by others. Could you please propose books or courses you found useful for this goal? We have the Gabrielsson & Weiner Pharmacokinetic and Pharmacodynamic Data Analysis, Concepts and Applications. Some have proposed the Owen & Fiedler-Kelly Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models, which I have not read yet. I already participated on the Sheiner/Rowland Advanced PK-PD Course in Waldhaus Sils, Switzerland and found it really useful, but I would need more details. We are located in Europe, so please do not propose US courses. Any suggestion would be welcome. Thank you for your help in advance. With regards, Gabriella Magyar Gabriella Magyar, PhD Pharmacokineticist, Biostatistician Developmental Drug Metabolism & Pharmacokinetics Gedeon Richter Plc. 1103 Budapest, Gyömrői út 19-21. Hungary Phone: +36 1 889 8613 Email: [email protected] <mailto:[email protected]> Website: http://www.richter.hu www.richter.hu Fővárosi Törvényszék Cégbírósága Cg. 01-10-040944 A jelen üzenet és annak bármely csatolmánya a Richter Gedeon Nyrt. tulajdonát képező bizalmas vagy szerzői jogi védelem alatt álló információkat tartalmazhat. A jelen üzenetet kizárólag a címzett, illetve az arra jogosultak használhatják fel. Ha a jelen üzenetnek nem Ön a címzettje, felhívjuk figyelmét, hogy az üzenet jogosulatlan terjesztése, másolása vagy a csatolmány tartalmával való visszaélés szigorúan tilos, és jogellenesnek minősülhet. Ha a jelen üzenetet tévedésből kapta, kérjük, haladéktalanul értesítse a küldő személyt és véglegesen törölje az üzenet eredeti példányát és minden másolatát, valamint semmisítse meg annak bármely kinyomtatott példányát. A Richter Gedeon Nyrt. nem vállal felelősséget a jelen üzenetben szereplő információk megfelelő és teljes körű továbbításáért, sem a kézhezvétellel kapcsolatos késedelemért. Óvja környezetét! Kérjük, ne nyomtasson feleslegesen! Company Registry Court of Budapest-Capital Regional Court No. Cg. 01-10-040944 This email and its attachments may contain Gedeon Richter Plc. proprietary information that is privileged, confidential or subject to copyright belonging to Gedeon Richter Plc. This email is intended solely for the use of the individual or entity to which it is addressed and others authorized to receive it. If you are not the intended recipient of this email, you are hereby notified that any distribution, copying or action taken in relation to the contents of and attachments to this email is strictly prohibited and may be unlawful. If you have received this email in error, please notify the sender immediately and permanently delete the original as well as any copy of this email and destroy any printout. Gedeon Richter Plc. is neither liable for the proper and complete transmission of the information contained in this email nor for any delay in its receipt. Please consider the environment before printing this e-mail.

From: [email protected] <[email protected]> On Behalf Of Magyar Gabriella dr. Sent: Friday, February 2, 2024 8:32 AM To: [email protected] Subject: [NMusers] books/courses for learning popPK, PK/PD Néhány olyan személy, aki megkapta ezt az üzenetet, ritkán kap e-mailt a(z) [email protected]<mailto:[email protected]> e-mail-címről. Miért fontos https://aka.ms/LearnAboutSenderIdentification CAUTION: This email originated from outside of Certara. Do not click links or open attachments unless you recognize the sender and know the content is safe. Dear NMUsers, I would like to learn popPK (and PK/PD in the long-term) to a level to be able to build models on my own. Now I'm on the level that I mostly understand the models built by others. Could you please propose books or courses you found useful for this goal? We have the Gabrielsson & Weiner Pharmacokinetic and Pharmacodynamic Data Analysis, Concepts and Applications. Some have proposed the Owen & Fiedler-Kelly Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models, which I have not read yet. I already participated on the Sheiner/Rowland Advanced PK-PD Course in Waldhaus Sils, Switzerland and found it really useful, but I would need more details. We are located in Europe, so please do not propose US courses. Any suggestion would be welcome. Thank you for your help in advance. With regards, Gabriella Magyar Gabriella Magyar, PhD Pharmacokineticist, Biostatistician Developmental Drug Metabolism & Pharmacokinetics [Gedeon_Richter_HOR_RGB_keretnelkul_500px] Gedeon Richter Plc. 1103 Budapest, Gyömrői út 19-21. Hungary Phone: +36 1 889 8613 Email: [email protected]<mailto:[email protected]> Website: http://www.richter.hu/ Fővárosi Törvényszék Cégbírósága Cg. 01-10-040944 A jelen üzenet és annak bármely csatolmánya a Richter Gedeon Nyrt. tulajdonát képező bizalmas vagy szerzői jogi védelem alatt álló információkat tartalmazhat. A jelen üzenetet kizárólag a címzett, illetve az arra jogosultak használhatják fel. Ha a jelen üzenetnek nem Ön a címzettje, felhívjuk figyelmét, hogy az üzenet jogosulatlan terjesztése, másolása vagy a csatolmány tartalmával való visszaélés szigorúan tilos, és jogellenesnek minősülhet. Ha a jelen üzenetet tévedésből kapta, kérjük, haladéktalanul értesítse a küldő személyt és véglegesen törölje az üzenet eredeti példányát és minden másolatát, valamint semmisítse meg annak bármely kinyomtatott példányát. A Richter Gedeon Nyrt. nem vállal felelősséget a jelen üzenetben szereplő információk megfelelő és teljes körű továbbításáért, sem a kézhezvétellel kapcsolatos késedelemért. Óvja környezetét! Kérjük, ne nyomtasson feleslegesen! Company Registry Court of Budapest-Capital Regional Court No. Cg. 01-10-040944 This email and its attachments may contain Gedeon Richter Plc. proprietary information that is privileged, confidential or subject to copyright belonging to Gedeon Richter Plc. This email is intended solely for the use of the individual or entity to which it is addressed and others authorized to receive it. If you are not the intended recipient of this email, you are hereby notified that any distribution, copying or action taken in relation to the contents of and attachments to this email is strictly prohibited and may be unlawful. If you have received this email in error, please notify the sender immediately and permanently delete the original as well as any copy of this email and destroy any printout. Gedeon Richter Plc. is neither liable for the proper and complete transmission of the information contained in this email nor for any delay in its receipt. Please consider the environment before printing this e-mail. This message (including any attachments) may contain confidential, proprietary, privileged and/or private information. The information is intended to be for the use of the individual or entity designated above. If you are not the intended recipient of this message, please notify the sender immediately, and delete the message and any attachments. Any disclosure, reproduction, distribution or other use of this message or any attachments by an individual or entity other than the intended recipient is prohibited.

________________________________ From: [email protected] <[email protected]> on behalf of Magyar Gabriella dr. <[email protected]> Sent: Friday, February 2, 2024 3:32 AM To: [email protected] <[email protected]> Subject: [External] [NMusers] books/courses for learning popPK, PK/PD Dear NMUsers, I would like to learn popPK (and PK/PD in the long-term) to a level to be able to build models on my own. Now I’m on the level that I mostly understand the models built by others. Could you please propose books or courses Dear NMUsers, I would like to learn popPK (and PK/PD in the long-term) to a level to be able to build models on my own. Now I’m on the level that I mostly understand the models built by others. Could you please propose books or courses you found useful for this goal? We have the Gabrielsson & Weiner Pharmacokinetic and Pharmacodynamic Data Analysis, Concepts and Applications. Some have proposed the Owen & Fiedler-Kelly Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models, which I have not read yet. I already participated on the Sheiner/Rowland Advanced PK-PD Course in Waldhaus Sils, Switzerland and found it really useful, but I would need more details. We are located in Europe, so please do not propose US courses. Any suggestion would be welcome. Thank you for your help in advance. With regards, Gabriella Magyar Gabriella Magyar, PhD Pharmacokineticist, Biostatistician Developmental Drug Metabolism & Pharmacokinetics [Gedeon_Richter_HOR_RGB_keretnelkul_500px] Gedeon Richter Plc. 1103 Budapest, Gyömrői út 19–21. Hungary Phone: +36 1 889 8613 Email: [email protected]<mailto:[email protected]> Website: https://urldefense.com/v3/__ http://www.richter.hu__;!!ODpDvJZr5w!DfnJmDt2w38TeIyWb6ZD92SoY2FZxB3s0O8Pk0XmNczmy3uFYY9RQMnas0BFnFdMTJlYzx4ohAIKGOGr8OmFzCyIFpc$ Fővárosi Törvényszék Cégbírósága Cg. 01-10-040944 A jelen üzenet és annak bármely csatolmánya a Richter Gedeon Nyrt. tulajdonát képező bizalmas vagy szerzői jogi védelem alatt álló információkat tartalmazhat. A jelen üzenetet kizárólag a címzett, illetve az arra jogosultak használhatják fel. Ha a jelen üzenetnek nem Ön a címzettje, felhívjuk figyelmét, hogy az üzenet jogosulatlan terjesztése, másolása vagy a csatolmány tartalmával való visszaélés szigorúan tilos, és jogellenesnek minősülhet. Ha a jelen üzenetet tévedésből kapta, kérjük, haladéktalanul értesítse a küldő személyt és véglegesen törölje az üzenet eredeti példányát és minden másolatát, valamint semmisítse meg annak bármely kinyomtatott példányát. A Richter Gedeon Nyrt. nem vállal felelősséget a jelen üzenetben szereplő információk megfelelő és teljes körű továbbításáért, sem a kézhezvétellel kapcsolatos késedelemért. Óvja környezetét! Kérjük, ne nyomtasson feleslegesen! Company Registry Court of Budapest-Capital Regional Court No. Cg. 01-10-040944 This email and its attachments may contain Gedeon Richter Plc. proprietary information that is privileged, confidential or subject to copyright belonging to Gedeon Richter Plc. This email is intended solely for the use of the individual or entity to which it is addressed and others authorized to receive it. If you are not the intended recipient of this email, you are hereby notified that any distribution, copying or action taken in relation to the contents of and attachments to this email is strictly prohibited and may be unlawful. If you have received this email in error, please notify the sender immediately and permanently delete the original as well as any copy of this email and destroy any printout. Gedeon Richter Plc. is neither liable for the proper and complete transmission of the information contained in this email nor for any delay in its receipt. Please consider the environment before printing this e-mail. ******************************************************************** This e-mail and any attachment hereto, is intended only for use by the addressee(s) named above and may contain legally privileged and/or confidential information. If you are not the intended recipient of this e-mail, any dissemination, distribution or copying of this email, or any attachment hereto, is strictly prohibited. If you receive this email in error please immediately notify me by return electronic mail and permanently delete this email and any attachment hereto, any copy of this e-mail and of any such attachment, and any printout thereof. Finally, please note that only authorized representatives of Regeneron Pharmaceuticals, Inc. have the power and authority to enter into business dealings with any third party. ********************************************************************

From: [email protected] <[email protected]> On Behalf Of Magyar Gabriella dr. Sent: Friday, February 2, 2024 12:32 AM To: [email protected] Subject: [EXTERNAL] [NMusers] books/courses for learning popPK, PK/PD Dear NMUsers, I would like to learn popPK (and PK/PD in the long-term) to a level to be able to build models on my own. Now I'm on the level that I mostly understand the models built by others. Could you please propose books or courses you found useful for this goal? We have the Gabrielsson & Weiner Pharmacokinetic and Pharmacodynamic Data Analysis, Concepts and Applications. Some have proposed the Owen & Fiedler-Kelly Introduction to Population Pharmacokinetic / Pharmacodynamic Analysis with Nonlinear Mixed Effects Models, which I have not read yet. I already participated on the Sheiner/Rowland Advanced PK-PD Course in Waldhaus Sils, Switzerland and found it really useful, but I would need more details. We are located in Europe, so please do not propose US courses. Any suggestion would be welcome. Thank you for your help in advance. With regards, Gabriella Magyar Gabriella Magyar, PhD Pharmacokineticist, Biostatistician Developmental Drug Metabolism & Pharmacokinetics [Gedeon_Richter_HOR_RGB_keretnelkul_500px] Gedeon Richter Plc. 1103 Budapest, Gyömrői út 19-21. Hungary Phone: +36 1 889 8613 Email: [email protected]<mailto:[email protected]> Website: http://www.richter.hu Fővárosi Törvényszék Cégbírósága Cg. 01-10-040944 A jelen üzenet és annak bármely csatolmánya a Richter Gedeon Nyrt. tulajdonát képező bizalmas vagy szerzői jogi védelem alatt álló információkat tartalmazhat. A jelen üzenetet kizárólag a címzett, illetve az arra jogosultak használhatják fel. Ha a jelen üzenetnek nem Ön a címzettje, felhívjuk figyelmét, hogy az üzenet jogosulatlan terjesztése, másolása vagy a csatolmány tartalmával való visszaélés szigorúan tilos, és jogellenesnek minősülhet. Ha a jelen üzenetet tévedésből kapta, kérjük, haladéktalanul értesítse a küldő személyt és véglegesen törölje az üzenet eredeti példányát és minden másolatát, valamint semmisítse meg annak bármely kinyomtatott példányát. A Richter Gedeon Nyrt. nem vállal felelősséget a jelen üzenetben szereplő információk megfelelő és teljes körű továbbításáért, sem a kézhezvétellel kapcsolatos késedelemért. Óvja környezetét! Kérjük, ne nyomtasson feleslegesen! Company Registry Court of Budapest-Capital Regional Court No. Cg. 01-10-040944 This email and its attachments may contain Gedeon Richter Plc. proprietary information that is privileged, confidential or subject to copyright belonging to Gedeon Richter Plc. This email is intended solely for the use of the individual or entity to which it is addressed and others authorized to receive it. If you are not the intended recipient of this email, you are hereby notified that any distribution, copying or action taken in relation to the contents of and attachments to this email is strictly prohibited and may be unlawful. If you have received this email in error, please notify the sender immediately and permanently delete the original as well as any copy of this email and destroy any printout. Gedeon Richter Plc. is neither liable for the proper and complete transmission of the information contained in this email nor for any delay in its receipt. Please consider the environment before printing this e-mail.