Hello NONMEM Users,
A SAEM code runwell until I tried to replace a block omega
matrix with a diagonal omega matrix. The the code crashed with
the following message:
[Window Title] nonmem.exe
[Main Instruction] nonmem.exe has stopped working
[Content] A problem caused the program to stop working
correctly. Please close the program.
[Close the program]
Another similar code where I made similar changes works well. I
tried to change iniial values for the diagonal omega, but it did
not work. Is it possible we have a bug?
Thanks,
Pavel
>
a potential bug
Your problem may be resolved by looking at item 4) in
ftp://nonmem.iconplc.com/Public/nonmem720/nm720_bug_list.pdf
Robert J. Bauer, Ph.D.
Vice President, Pharmacometrics, R&D
ICON Development Solutions
7740 Milestone Parkway
Suite 150
Hanover, MD 21076
Tel: (215) 616-6428
Mob: (925) 286-0769
Email: [email protected]<mailto:[email protected]>
Web: http://www.iconplc.com/
Quoted reply history
From: [email protected] [mailto:[email protected]] On
Behalf Of [email protected]
Sent: Tuesday, April 02, 2013 5:39 PM
To: [email protected]
Cc: [email protected]
Subject: [NMusers] a potential bug
Hello NONMEM Users,
A SAEM code runwell until I tried to replace a block omega
matrix with a diagonal omega matrix. The the code crashed with
the following message:
[Window Title] nonmem.exe
[Main Instruction] nonmem.exe has stopped working
[Content] A problem caused the program to stop working
correctly. Please close the program.
[Close the program]
Another similar code where I made similar changes works well. I
tried to change iniial values for the diagonal omega, but it did
not work. Is it possible we have a bug?
Thanks,
Pavel
>
Dear Robert,
The code already has CONSTRAIN=0 in the $EST step. CONSTRAIN=0 fixed crashes
in most jobs. Some jobs still terminate. In one code it terminates
immideately. In another core it terminates after the firt iteration. It looks
less likely that $SIZES is causing this issue now.
Thanks,
Pavel
Quoted reply history
----- Original Message -----
From: "Bauer, Robert"
Date: Tuesday, April 2, 2013 6:57 pm
Subject: RE: [NMusers] a potential bug
To: "[email protected]"
Cc: "[email protected]"
> Your problem may be resolved by looking at item 4) in
>
> ftp://nonmem.iconplc.com/Public/nonmem720/nm720_bug_list.pdf
>
>
> Robert J. Bauer, Ph.D.
> Vice President, Pharmacometrics, R&D
> ICON Development Solutions
> 7740 Milestone Parkway
> Suite 150
> Hanover, MD 21076
> Tel: (215) 616-6428
> Mob: (925) 286-0769
> Email: [email protected]
> Web: www.iconplc.com
>
> From: [email protected] [mailto:owner-
> [email protected]] On Behalf Of [email protected]
> Sent: Tuesday, April 02, 2013 5:39 PM
> To: [email protected]
> Cc: [email protected]
> Subject: [NMusers] a potential bug
>
> Hello NONMEM Users,
>
> A SAEM code runwell until I tried to replace a block omega
> matrix with a diagonal omega matrix. The the code crashed with
> the following message:
>
> [Window Title] nonmem.exe
> [Main Instruction] nonmem.exe has stopped working
> [Content] A problem caused the program to stop working
> correctly. Please close the program.
> [Close the program]
>
> Another similar code where I made similar changes works well. I
> tried to change iniial values for the diagonal omega, but it did
> not work. Is it possible we have a bug?
> Thanks,
> Pavel
> >
>
>