Re: Log Transformed AST

From: William Denney Date: July 23, 2019 technical Source: mail-archive.com
Hi Ranita, Duy is correct. NONMEM is based on FORTRAN, so usually the mathematical functions and operators are borrowed from FORTRAN: https://gcc.gnu.org/onlinedocs/gfortran/LOG.html Thanks, Bill
Quoted reply history
> On Jul 22, 2019, at 19:49, Duy Tran <[email protected]> wrote: > > If you desire to log transform by base 10 instead of e, use LOG10 in NONMEM > instead of LOG > >> On Mon, Jul 22, 2019 at 4:43 PM Ranita Kirubakaran >> <[email protected]> wrote: >> Dear all, >> >> I am a PhD student working on NONMEM as a new user. I am working on external >> evaluation of some of the selected published population PK models. While >> trying to implement one of the models in NONMEM, I realised that if I code >> log-transformed aspartate aminotransferase (LAST) as LAST = LOG(AST), the >> sdtab output is giving me the In(AST) value instead of a LOG(AST) value. >> Was wondering if NONMEM interprets all Log (x) as Log e (x) instead of Log >> 10 (x)? >> >> Thank you. >> >> Best Regards, >> Ranita Kirubakaran >> PhD Candidate >> >> >> Ranita Kirubakaran >> >> PhD Candidate >> St Vincent’s Clinical School | UNSW Sydney >> Department of Clinical Pharmacology and Toxicology >> Therapeutics Centre | Level 2 Xavier Building >> St Vincent’s Hospital >> 390 Victoria Street | Darlinghurst NSW 2010 | Australia >> E [email protected] | P +61 (2) 8382 2199 | F +61 (2) 8382 >> 2724 >> > >
Jul 22, 2019 Ranita Kirubakaran Log Transformed AST
Jul 22, 2019 Duy Tran Re: Log Transformed AST
Jul 23, 2019 William Denney Re: Log Transformed AST
Jul 23, 2019 Ranita Kirubakaran Re: Log Transformed AST