Log Transformed AST

From: Ranita Kirubakaran Date: July 22, 2019 technical Source: mail-archive.com
Dear all, I am a PhD student working on NONMEM as a new user. I am working on external evaluation of some of the selected published population PK models. While trying to implement one of the models in NONMEM, I realised that if I code log-transformed aspartate aminotransferase (LAST) as LAST = LOG(AST), the sdtab output is giving me the In(AST) value instead of a LOG(AST) value. Was wondering if NONMEM interprets all Log (x) as Log e (x) instead of Log 10 (x)? Thank you. Best Regards, Ranita Kirubakaran PhD Candidate Ranita Kirubakaran PhD Candidate St Vincent’s Clinical School | UNSW Sydney Department of Clinical Pharmacology and Toxicology Therapeutics Centre | Level 2 Xavier Building St Vincent’s Hospital 390 Victoria Street | Darlinghurst NSW 2010 | Australia E [email protected]<mailto:[email protected]> | P +61 (2) 8382 2199 | F +61 (2) 8382 2724
Jul 22, 2019 Ranita Kirubakaran Log Transformed AST
Jul 22, 2019 Duy Tran Re: Log Transformed AST
Jul 23, 2019 William Denney Re: Log Transformed AST
Jul 23, 2019 Ranita Kirubakaran Re: Log Transformed AST