Calculation of half life
Dear all,
I am looking for ways to calculate t[1/2,lamda,z] the elimination phase
half life, using a 3-compartment model. ADVAN 12 and TRANS6 seems to be a
way. However, I am using the intercompartment clearance and volumes based
parameterization, e.g. Q3,V3 etc..
half.life = log(2)/gamma
Could anyone please share NONMEM code to compute the half-life based on
gamma?
Thanks so much in advance.
Best regards,
Santosh