Predicting body weight as a function of gestational age
Dear All,
I am working on a PK model in neonates, infants, and children (postnatal
ages 0-12 years). I am to the point of running simulations and was
looking for a model to predict body weight as a function of gestational
age. I could simply resample from the data used to construct the PK
model or build a model based on the data in hand (n~200), but I was
looking for a published model (based on a larger sample size) that might
be used as a point of reference. As the relative difference between
gestational age and postnatal age diminishes in older children models of
body weight as a function of postnatal age for children >2 years old
could also be useful.
Thanks for any suggestions you might have.
Cheers... Brian
Brian M. Sadler, Ph.D.
Sr Scientific Director
ICON Development Solutions
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