Asterisks in simulated data after changes to maximum observation records and BUFFER

From: Paul Hutson Date: August 13, 2009 technical Source: mail-archive.com
Title: Paul R I am attempting to generate 100 iterations of a concentration curve for multiple doses in a single individual. In order to reflect the input of the extended release dosage form from the dissolution data, I have multiple infusions into the gut representing the amount released in each of these units of time based on the dissolution data. For 14 doses, then, I am reproducing this, and the data file is quite long (687 records). I have therefore had to increase NSIZES with respect to the number of observations, as well as increasing buffers 1,2, and 6. I will need to import the results into R, since excel can't take 687X100 lines of output. However, regardless of whether I look at my .txt output, or importing it as far as I can into Excel, the output includes asterisks ID TIME CMPT IPRE DV PRED RES WRES 1.0000E+00 0.0000E+00 1.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 1.0000E+00 2.5000E-01 2.0000E+00 1.1193E-05 -5.6330E-02 3.0897E-05 -5.6361E-02 0.0000E+00 1.0000E+00 2.5000E-01 3.0000E+00 3.6747E-09 3.6747E-09 1.0143E-08 -6.4683E-09 0.0000E+00 1.0000E+00 2.5000E-01 1.0000E+00 1.1193E-05 0.0000E+00 3.0897E-05 0.0000E+00 0.0000E+00 1.0000E+00 5.0000E-01 2.0000E+00 *********** *********** *********** *********** 0.0000E+00 1.0000E+00 5.0000E-01 3.0000E+00 *********** *********** *********** *********** 0.0000E+00 Can anyone explain why I am getting the asterisks in the output (even with only one simulation? Everything was fine before I messed with the buffers (relevant part of SIZES below): C NO: MAX NO. OF OBSERVATION RECORDS / INDIVIDUAL RECORD C IF NO IS CHANGED, ALSO RECOMPILE NM-TRAN, NM-TRAN LIBRARY PARAMETER (NO=750) ... C LIM1: SIZE OF BUFFER 1 PARAMETER (LIM1=800) C LIM2: SIZE OF BUFFER 2 PARAMETER (LIM2=800) C LIM3: SIZE OF BUFFER 3 PARAMETER (LIM3=200) C LIM4: SIZE OF BUFFER 4 PARAMETER (LIM4=50) C LIM5: SIZE OF BUFFER 5 PARAMETER (LIM5=200) C LIM6: SIZE OF BUFFER 6 PARAMETER (LIM6=800) C LIM7: SIZE OF BUFFER 7 PARAMETER (LIM7=2) C LIM8: SIZE OF BUFFER 8 PARAMETER (LIM8=200) C LIM11: SIZE OF BUFFER 11 PARAMETER (LIM11=25) C LIM13: SIZE OF BUFFER 13 PARAMETER (LIM13=1) C LIM15: SIZE OF BUFFER 15 PARAMETER (LIM15=1) C LIM16: SIZE OF BUFFER 16 PARAMETER (LIM16=400) Thanks very much Paul -- Paul R. Hutson, Pharm.D. Associate Professor UW School of Pharmacy 777 Highland Avenue Madison WI 53705-2222 Tel 608.263.2496 Fax 608.265.5421 Pager 608.265.7000, p7856
Aug 13, 2009 Paul Hutson Asterisks in simulated data after changes to maximum observation records and BUFFER
Aug 14, 2009 Paul Hutson Re: Asterisks in simulated data after changes to maximum observation records and BUFFER