Asterisks in simulated data after changes to maximum observation records and BUFFER

From: Paul Hutson Date: August 13, 2009 technical Source: cognigen.com
I am attempting to generate 100 iterations of a concentration curve for multiple doses in a single individual. In order to reflect the input of the extended release dosage form from the dissolution data, I have multiple infusions into the gut representing the amount released in each of these units of time based on the dissolution data. For 14 doses, then, I am reproducing this, and the data file is quite long (687 records). I have therefore had to increase NSIZES with respect to the number of observations, as well as increasing buffers 1,2, and 6. I will need to import the results into R, since excel can't take 687X100 lines of output. However, regardless of whether I look at my .txt output, or importing it as far as I can into Excel, the output includes asterisks ID TIME CMPT IPRE DV PRED RES WRES 1.0000E+00 0.0000E+00 1.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 0.0000E+00 1.0000E+00 2.5000E-01 2.0000E+00 1.1193E-05 -5.6330E-02 3.0897E-05 -5.6361E-02 0.0000E+00 1.0000E+00 2.5000E-01 3.0000E+00 3.6747E-09 3.6747E-09 1.0143E-08 -6.4683E-09 0.0000E+00 1.0000E+00 2.5000E-01 1.0000E+00 1.1193E-05 0.0000E+00 3.0897E-05 0.0000E+00 0.0000E+00 1.0000E+00 5.0000E-01 2.0000E+00 *********** *********** *********** *********** 0.0000E+00 1.0000E+00 5.0000E-01 3.0000E+00 *********** *********** *********** *********** 0.0000E+00 Can anyone explain why I am getting the asterisks in the output (even with only one simulation? Everything was fine before I messed with the buffers (relevant part of SIZES below): C NO: MAX NO. OF OBSERVATION RECORDS / INDIVIDUAL RECORD C IF NO IS CHANGED, ALSO RECOMPILE NM-TRAN, NM-TRAN LIBRARY PARAMETER (NOu0) ... C LIM1: SIZE OF BUFFER 1 PARAMETER (LIM10) C LIM2: SIZE OF BUFFER 2 PARAMETER (LIM20) C LIM3: SIZE OF BUFFER 3 PARAMETER (LIM3 0) C LIM4: SIZE OF BUFFER 4 PARAMETER (LIM4P) C LIM5: SIZE OF BUFFER 5 PARAMETER (LIM5 0) C LIM6: SIZE OF BUFFER 6 PARAMETER (LIM60) C LIM7: SIZE OF BUFFER 7 PARAMETER (LIM7=2) C LIM8: SIZE OF BUFFER 8 PARAMETER (LIM8 0) C LIM11: SIZE OF BUFFER 11 PARAMETER (LIM11%) C LIM13: SIZE OF BUFFER 13 PARAMETER (LIM13=1) C LIM15: SIZE OF BUFFER 15 PARAMETER (LIM15=1) C LIM16: SIZE OF BUFFER 16 PARAMETER (LIM16@0) Thanks very much Paul -- Paul R Paul R. Hutson, Pharm.D. Associate Professor UW School of Pharmacy 777 Highland Avenue Madison WI 53705-2222 Tel 608.263.2496 Fax 608.265.5421 Pager 608.265.7000, p7856