RE: calculation of AUC
Dear Ethan,
You need to provide more information on how you plan to calculate AUC
otherwise the question can't be answered. It is of course possible to
calculate the AUC without any influence of the sampling frequency. You
should be able to find examples of how to do this in the NMusers archive.
See for example the answer from Mats Karlsson in this thread
( http://nonmem.org/nonmem/nm/98apr032002.html).
Kind regards,
Martin Bergstrand, MSc, PhD student
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Department of Pharmaceutical Biosciences,
Uppsala University
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P.O. Box 591
SE-751 24 Uppsala
Sweden
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<mailto:[email protected]> [email protected]
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Work: +46 18 471 4639
Mobile: +46 709 994 396
Fax: +46 18 471 4003
Quoted reply history
From: [email protected] [mailto:[email protected]] On
Behalf Of Ethan Wu
Sent: den 20 mars 2009 13:05
To: [email protected]
Subject: [NMusers] calculation of AUC
Hi all, to calculate AUC of one of the compartments using ADVAN6, if it is a
fixed time interval, will the AUC be influenced by the frequncy of sampling
of the dataset within this interval or not?
thanks