RE: automating the writing of models
Carlos I'm not sure what you want to do. DruDevo (www.drudevo.com, don't know if they are still around) has a web site that seems to imply they do some of this:
Ø
Automated structural
model search
Automated statistical
model search
Automated multi level
covariate search
Ø
Automated multi level
backwards deletion
.
Automated multi level
covariate search
But, I really don't know anything about it. I think that Ken Kawalski's Wald test covariate search approach does some automated control file writing as well, limited (I think) to covariate relationships. Of course, I have to mention my own, which isn't generally available (www.nextlevelsolns.com) but does automate writing control files and searching for the optimal solution.
Mark Sale MD
Next Level Solutions, LLC
www.NextLevelSolns.com
919-846-9185
> -------- Original Message -------- Subject: [NMusers] automating the writing of models From: "Bachman, William (MYD)" <[EMAIL PROTECTED]> Date: Mon, March 31, 2008 11:04 am To: "Dr. Carlos Hoyo" <[EMAIL PROTECTED]>,
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> [email protected]
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> Carlos, The closest thing, that I am aware of, to automated models is the Control File Wizards found in PDx-Pop. PDx-Pop provides a graphical user interface to NONMEM that includes creating and running control files (singly or in batch mode), automated diagnostic plots for the runs, and automated model evaluation methods. The Control File Wizards create control files graphically by selecting options you want to include in your model, number of compartments, method of drug administration, parameterization (CL/V vs micro-, macro-constant), etc. You enter parameter values in tables on the screen and can specify estimation methods and table options. I will send you screen shots off-line to give you a better idea. (nmusers has a limit on the size of an email you can send). There are two wizards: one for the standard models (advans 1-4, 10-12) and another for user-written models (advans 5-9). for more information see:
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> http://www.icondevsolutions.com/pdxpop.htm
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> William J. Bachman, Ph.D. Director, Pharmacometrics R&D Icon Development Solutions 6031 University Blvd., Suite 300 Ellicott City, MD 21043 Office 410-696-3002 Cell 301-467-8635 -----Original Message----- From:
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> owner-nmusers @globomaxnm.com
>
> [mailto:
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> owner-nmusers @globomaxnm.com
>
> ] On Behalf Of Dr. Carlos Hoyo Sent: Wednesday, March 19, 2008 10:10 PM To:
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> nmusers @globomaxnm.com
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> Subject: [NMusers] archive of this list Dear all, How can one access an archive of all the emails of this list? I am looking for tools for automating the writing of models? Is it included in wings? (where). Thanks, Carlos Hoyo
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> capitanmacintosh @gmail.com
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