automating the writing of models

Carlos, The closest thing, that I am aware of, to automated models is the Control File Wizards found in PDx-Pop. PDx-Pop provides a graphical user interface to NONMEM that includes creating and running control files (singly or in batch mode), automated diagnostic plots for the runs, and automated model evaluation methods. The Control File Wizards create control files graphically by selecting options you want to include in your model, number of compartments, method of drug administration, parameterization (CL/V vs micro-, macro-constant), etc. You enter parameter values in tables on the screen and can specify estimation methods and table options. I will send you screen shots off-line to give you a better idea. (nmusers has a limit on the size of an email you can send). There are two wizards: one for the standard models (advans 1-4, 10-12) and another for user-written models (advans 5-9). for more information see: http://www.icondevsolutions.com/pdxpop.htm William J. Bachman, Ph.D. Director, Pharmacometrics R&D Icon Development Solutions 6031 University Blvd., Suite 300 Ellicott City, MD 21043 Office 410-696-3002 Cell 301-467-8635