PK/PD models to describe anti-ancer drug effect on the tumor volume

Dear NMusers, Does anyone aware any good published example (or non-public if you are willing to share) of modeling the anti-cancer drug effect on the tumor volume in nude mice model? And how this is normally used in the human dose projection, and any published work of such? Please advice. Thank you very much. Patrick --------------------------------- Be a better friend, newshound, and know-it-all with Yahoo! Mobile. Try it now.