batches with different half-life - linear PK
Hello NONMEM Users,
Sometimes the same subjects receive the same drug from different batches.
Potentially, half-life can be different accross batches. Theoretically, it is
easy to model if PKis linear because NONMEM superimposes single-dose processes
to obtain predicted concentrations for multiple doses. Does enyone know how to
implement it in NONMEM? Are there any classes or publications which can help?
Thanks!
Pavel