RE: MAXIDS=10000

From: "Ludden, Thomas (MYD)" luddent@iconus.com Subject: RE: [NMusers] MAXIDS=10000 Date: Fri, 1 Dec 2006 11:58:13 -0500 Mark and Nick, I checked the reference copy of NONMEM V 1.1 and the Master CD used for the distribution of NONMEM V 1.1 dated 18 March 2005 and both have LIM6=200 in NSIZES. Perhaps the LIM6 value in NONMEM V 1.1 was changed from 200 to 600 for your respective installations. As already noted, the default value for this parameter was increased to 400 in both the NONMEM VI 1.0 Beta and the released version of NONMEM VI 1.0. Regarding MAXIDS: To sort the individual contributions of the objective function value prior to summation and to store these individual values in a common for later output by the user, it is necessary to provide a maximum size for the associated arrays. This is a limitation of FORTRAN 77. While it would have been possible to circumvent the limit when sorting was not selected, it would still have been necessary for storing these values for eventual output by the user. I would agree that a larger value should have been chosen. We have already had to increase the value from 1000 to 2000 for a current analysis. When NONMEM VI is first installed, users may want to adjust this value, the value for LIM6 and any other parameter values in SIZES to meet their specific needs or to match the values they have been using in NONMEM V. Tom Ludden Icon Development Solutions