Re: sequential PKPD modeling
From: "Jiang, Xuemin" xjiang1@medicine.bsd.uchicago.edu
Subject: Re: [NMusers] sequential PKPD modeling
Date: Thu, 26 Oct 2006
Dear NONMEM users,
I would like to make my question clear. To my understanding, simultaneous analysis of PKPD
data is a better analysis especially for the sparse PK data, because the PD data can support
PK data analysis. I am wondering whether it is possible that the increasing on the CL of
drug A (in the following email) could be a consequence of PD effect of drug B rather then
a real PK effect in a simultaneous PKPD modeling.
Jim Jiang