RE: NONMEM questions
From: Johan.Rosenborg@astrazeneca.com
Subject: RE: [NMusers] NONMEM questions
Date: Mon, 21 Mar 2005 10:33:56 +0100
Dear Ji Ping,
I agree with Liping that subdividing the problem could be a
good way forward. To start with, however, I think you should
check your data file - have you accounted for the repeat dose
situation? If not add a steady-state (SS) or Additional Dose
(ADDL) and Interdose Interval (II) variables in the data set
(cf. NM User Guide part V, page 57 and c:\NMV\HELP\SSDOSE.DAT
or c:\NMV\HELP\ADDL.DAT).
/ Johan
Johan Rosenborg, Ph.D.
Senior Pharmacokineticist, Clinical Pharmacology
Medical Science Sweden
AstraZeneca R&D Lund
SE-221 87 Lund, Sweden