Re: NONMEM questions

From: Liping Zhang ZHANG_LIPING@lilly.com Subject: Re: [NMusers] NONMEM questions Date: Fri, 18 Mar 2005 13:13:00 -0500 since the two population have many different PK parameters (Cl, V, Tlag, additive error, etc), why don't you fit them separately, establish good structural models and get the estimation run successfully, then check if they are similar enough to fit them together and use Type as a covariate? Doing so will also give you an idea on which parameter to put Type as a covariate. BTW, I do not see zero absorption in the control file. best regards, Liping Liping Zhang, PhD